Application of the RCOG Risk Assessment Model for Evaluating Postpartum Venous Thromboembolism in Chinese Women: A Case-Control Study

07 July 2021: Clinical Research

Ying-Zhou Ge ^123ACDEF , Chen Zhang ^123CD , Yan-Qing Cai ^123ABE* , He-Feng Huang ^123AEG**

DOI: 10.12659/MSM.929904

Med Sci Monit 2021; 27:e929904

Table 2 Risk factors for postpartum VTE contained in the RCOG risk assessment model.

Variable*	VTE group**n=38	Control group**n=152	χ2	p Value

Previous VTE not related to major surgery	4 (10.53)	0 (0.00)	10.35	0.001
Medical comorbidities	2 (5.26)	3 (1.97)	1.19	0.276
Family history of VTE	8 (21.05)	10 (6.58)	6.68	0.010
Known low-risk thrombophilia	4 (10.53)	2 (1.32)	6.03	0.014
Age >35 years	14 (36.84)	25 (16.45)	7.33	0.007
Obesity			0.05	0.978
BMI ≥30	1 (2.63)	5 (3.29)
BMI ≥40	0 (0.00)	1 (0.66)
Parity >3	1 (2.63)	4 (2.63)	0.00	1.000
Smoker	3 (7.89)	2 (1.32)	3.99	0.046
Gross varicose veins	1 (2.63)	1 (0.66)	0.97	0.324

Pre-eclampsia	2 (5.26)	10 (6.58)	0.09	0.766
Multiple pregnancy	4 (10.53)	3 (1.97)	5.03	0.025
Cesarean section in labor	18 (47.37)	20 (13.16)	19.46
Elective cesarean section	17 (44.74)	71 (46.71)	0.05	0.827
Mid-cavity or rotational operative delivery	0 (0.00)	9 (5.92)	1.23	0.267
Prolonged labor (>24 hours)	0 (0.00)	3 (1.97)	0.00	1.000
PPH (>1 litre or transfusion)	1 (2.63)	5 (3.29)	0.04	0.836
Preterm birth	4 (10.53)	5 (3.29)	3.17	0.075

Surgical procedure in pregnancy or puerperium	6 (15.79)	4 (2.63)	8.25	0.004
Current systemic infection	4 (10.53)	7 (4.61)	1.85	0.174
Immobility, dehydration	2 (5.26)	2 (1.32)	1.97	0.161
VTE – venous thromboembolism; BMI – body mass index; PPH – postpartum hemorrhage. ^* Previous VTE provoked by major surgery, known high-risk thrombophilia, stillbirth, and hyperemesis are also factors contained in the RCOG risk assessment model, but they did not exist in our study population, thus they are not included in the table. ^** data are presented as number (percentage).