05 July 2021: Clinical Research
Identification and Characterization of Non-Coding RNAs in Thymoma
Guanglei Ji 1AE , Rongrong Ren 2BCDF , Xichao Fang 3BCDF*DOI: 10.12659/MSM.929727
Med Sci Monit 2021; 27:e929727
Table 3 Summary of detected fusion genes and their statistics (arranged by significance level).
| S. No. | Detected fusion genes | chr1 | Breakpoint1 | chr2 | Breakpoint2 | Strands (1/2) | Thymoma samples | Healthy samples |
|---|---|---|---|---|---|---|---|---|
| 1 | KMT2A-MAML2 | 11 | 118436492 | 11 | 95976698 | (+/−) | 9/25 | 1/25 |
| 2 | HADHB -REEP1 | 2 | 26502983 | 2 | 86491164 | (+/−) | 6/25 | 0/25 |
| 3 | COQ3-CGA | 6 | 99842080 | 6 | 87804824 | (+/+) | 6/25 | 1/25 |
| 4 | MCM4-SNTB1 | 8 | 48878682 | 8 | 48878526 | (+/−) | 5/25 | 0/25 |
| 5 | IFT140-ACTN4 | 16 | 1616292 | 19 | 39138547 | (+/−) | 4/25 | 0/25 |
| 6 | ZAP70-GLI2 | 2 | 98349346 | 2 | 121555044 | (−/−) | 6/25 | 2/25 |
| 7 | UBR1-FLNB | 15 | 43340689 | 3 | 58104716 | (+/−) | 6/25 | 3/25 |
| 8 | PREPL-P4HTM | 2 | 44569556 | 3 | 49038871 | (−/+) | 4/25 | 3/25 |
| 9 | R3HDM1-KATNA1 | 2 | 136418963 | 6 | 149959696 | (+/−) | 4/25 | 3/25 |
| 10 | ANXA6-SLC36A3 | 5 | 150496688 | 5 | 150675829 | (−/−) | 4/25 | 3/25 |
| 11 | ADCY3-KDM3A | 2 | 25065253 | 2 | 86684194 | (+/−) | 3/25 | 3/25 |
| 12 | EP300-PRR5 | 22 | 41560134 | 22 | 45110471 | (+/+) | 3/25 | 3/25 |
| 13 | DTNB-PSIP1 | 2 | 25600422 | 9 | 15510115 | (+/+) | 3/25 | 2/25 |
| 14 | PDS5B-IL17RB | 13 | 33233417 | 3 | 53890871 | (+/+) | 3/25 | 2/25 |
| 15 | CLIP4-C5 | 2 | 29358532 | 9 | 123732529 | (+/−) | 3/25 | 1/25 |
| 16 | EML4-TMEM163 | 2 | 42396776 | 2 | 135309662 | (+/−) | 3/25 | 1/25 |
| 17 | MFSD2B-DNMT3A | 2 | 24236155 | 2 | 25458576 | (−/+) | 3/25 | 1/25 |
| 18 | R3HDM1-WDR6 | 2 | 136482840 | 3 | 49053386 | (−/−) | 3/25 | 1/25 |
| 19 | PIGS-SLC46A1 | 17 | 26898546 | 17 | 26733228 | (−/−) | 3/25 | 1/25 |
| 20 | ATP9B-SYNPR | 18 | 76903860 | 3 | 63466508 | (+/+) | 3/25 | 1/25 |
| 21 | ARHGEF4-USP45 | 2 | 131785518 | 6 | 99936076 | (−/+) | 2/25 | 1/25 |