23 June 2020: Database Analysis
Bioinformatics-Based Study to Investigate Potential Differentially Expressed Genes and miRNAs in Pediatric Sepsis
Kexin Xie 1BE* , Shan Kong 1CE* , Fuxing Li 1DF , Yulin Zhang 1CD , Jing Wang 2DF , Weidong Zhao 1AG*DOI: 10.12659/MSM.923881
Med Sci Monit 2020; 26:e923881
Table 2 Screening DEGs in pediatric sepsis patients by integrated microarray.
| DEGs | Gene terms |
|---|---|
| Upregulated | MMP8 CD177 OLFM4 ARG1 MCEMP1 ANXA3 HP RETN LTF ANKRD22 MMP9 LCN2 VNN1 GPR84 CEACAM1 S100A12 CA4 CYSTM1 CLEC4D SOCS3 TCN1 RGL4 GYG1 PFKFB3 FCGR1B S100P IRAK3 MGAM LILRA5 IL18R1 LRG1 ADGRG3 DYSF ALPL PFKFB2 HK3 CKAP4 PGLYRP1 CD163 ZDHHC19 PADI4 TLR5 PGD NLRC4 SERPINB1 SLC2A3 GADD45A KIF1B ACSL1 ADM BCL6 SORT1 PROK2 STOM SAMSN1 PSTPIP2 PYGL B4GALT5 FCER1G ACER3 C3AR1 CST7 MKNK1 RNASE2 TNFAIP6 IL1RN SIPA1L2 THBS1 FKBP5 IL18RAP SLC22A4 OSCAR PLBD1 CDA FLOT1 SIGLEC5 FAR2 UGCG PGS1 SERPINA1 FAM129A ELANE DEFA4 TSPO ITGAM LILRA3 NCF4 CD55 BASP1 ORM1 ETS2 SIRPA FLOT2 ATP9A MARCKS TLR8 RAB31 FFAR2 CEBPD CCR1 PLIN3 AQP9 CEACAM6 C5AR1 FPR2 CTSD MPO SLC25A37 SEMA4A AGTRAP STXBP2 MSRB1 TRIB1 ALOX5AP HCK TIMP1 GK FGR SPI1 RHAG ADGRE1 MMP25 CD14 CSF3R LILRB3 CREB5 GCA ALPK1 GRN KCNJ2 FPR1 NBEAL2 NAMPT PRKCD CLEC1B STX3 MTF1 NFE2 CEBPB P2RX1 UBE2H ZYX IDI1 FES DENND3 RNF24 G6PD VPS9D1 RALB VNN2 ASAP1 MS4A3 CTSA GRINA GNA15 STX11 BAZ1A SHKBP1 RHOG IL1B |
| Downregulated | CD6 GIMAP1 FCRLA KDM2B PIK3IP1 CD8A SKAP1 PCED1B BCAS4 RPL22 PKIA LEF1 DYRK2 SPOCK2 NMT2 ETS1 LDHB CLEC2D PRKCQ-AS1 CD96 ATM FAM102A ITM2A MAL CD3G CD27 CCR7 C12orf57 AUTS2 HLA-DMB PAQR8 RFTN1 EVL PLEKHA1 CLC IL7R PRKCH PASK CD3D FCMR FAM117B CCL5 TRAF5 THEMIS RNF125 ABLIM1 CD2 BCL11B GPR183 RASGRP1 SAMD3 GZMK CD247 NELL2 GZMA TRAT1 GPR18 SH2D1A LRRN3 KLRB1 KLRF1 |
| DEGs – differentially expressed genes. | |