Apoptosis Activation in Thyroid Cancer Cells by Jatrorrhizine-Platinum(II) Complex via Downregulation of PI3K/AKT/Mammalian Target of Rapamycin (mTOR) Pathway

Related articles

22 Aug 2022 : Review article

Programmed Cell Death in Diabetic Nephropathy: A Review of Apoptosis, Autophagy, and Necroptosis

Nour S. Erekat,

DOI: 10.12659/MSM.937766

06 Jan 2020 : Laboratory Research

Lysophosphatidic Acid Receptor 5 (LPAR5) Plays a Significance Role in Papillary Thyroid Cancer via Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin (mTOR) Pathway

Cheng-Yong Wu, Chen Zheng, [...] Er-Jie Xia, Rui-Da Quan, Jing Hu, Xiao-Hua Zhang, Ru-Tian Hao - Show fewer authors

DOI: 10.12659/MSM.919820

28 Feb 2020 : Laboratory Research

Synaptotagmin 12 (SYT12) Gene Expression Promotes Cell Proliferation and Progression of Lung Adenocarcinoma and Involves the Phosphoinositide 3-Kinase (PI3K)/AKT/Mammalian Target of Rapamycin (mTOR) Pathway

Kaichao Liu, Jing Luo, [...] Chenye Shao, Zhijian Ren, Sai Sun, Yihao Zhu, Hai Zhou, Zhisheng Jiang, Xiaokun Li, Wenfeng Gu, Youtao Xu, Yong Qiang, Binhui Ren, Lin Xu, Haiwei Wu, Yi Shen - Show fewer authors

DOI: 10.12659/MSM.920351

19 May 2020 : Laboratory Research

Effect of Oleanolic Acid on Apoptosis and Autophagy of SMMC-7721 Hepatoma Cells

Weipeng Zhou, Xianjun Zeng, [...] Xiaoping Wu - Show fewer authors

DOI: 10.12659/MSM.921606

28 Jun 2020 : Laboratory Research

Down-Regulation of the Mammalian Target of Rapamycin (mTOR) Pathway Mediates the Effects of the Paeonol-Platinum(II) Complex in Human Thyroid Carcinoma Cells and Mouse SW1736 Tumor Xenografts

Ling He, Song Guo, [...] Taiyang Zhu, Chen Chen, Kun Xu - Show fewer authors

DOI: 10.12659/MSM.922561

06 Dec 2019 : Animal Research

Resveratrol Protects the Myocardium in Sepsis by Activating the Phosphatidylinositol 3-Kinases (PI3K)/AKT/Mammalian Target of Rapamycin (mTOR) Pathway and Inhibiting the Nuclear Factor-κB (NF-κB) Signaling Pathway

Xiuling Shang, Kaiyang Lin, [...] Rongguo Yu, Pengli Zhu, Yingrui Zhang, Ling Wang, Jingqing Xu, Kaihua Chen - Show fewer authors

DOI: 10.12659/MSM.918369

27 Oct 2019 : Laboratory Research

Three-Dimensional Printed Titanium Scaffolds Enhance Osteogenic Differentiation and New Bone Formation by Cultured Adipose Tissue-Derived Stem Cells Through the IGF-1R/AKT/Mammalian Target of Rapamycin Complex 1 (mTORC1) Pathway

Xiaoyu Zhou, Dongjie Zhang, [...] Mengling Wang, Ding Zhang, Yisheng Xu - Show fewer authors

DOI: 10.12659/MSM.918517

02 Oct 2019 : Clinical Research

Tivantinib Hampers the Proliferation of Glioblastoma Cells via PI3K/Akt/Mammalian Target of Rapamycin (mTOR) Signaling

Yukun Wu, Zhizhang Li, [...] Lijuan Zhang, Guiyang Liu - Show fewer authors

DOI: 10.12659/MSM.919319

25 Mar 2019 : Clinical Research

Neuro-Protective Role of Metformin in Patients with Acute Stroke and Type 2 Diabetes Mellitus via AMPK/Mammalian Target of Rapamycin (mTOR) Signaling Pathway and Oxidative Stress

Min Zhao, Xiao Wan Li, [...] De Z. Chen, Fang Hao, Shu X. Tao, Hai Yan Yu, Rui Cheng, Hong Liu - Show fewer authors

DOI: 10.12659/MSM.911250

03 Jan 2019 : Laboratory Research

Everolimus Reverses Palbociclib Resistance in ER+ Human Breast Cancer Cells by Inhibiting Phosphatidylinositol 3-Kinase(PI3K)/Akt/Mammalian Target of Rapamycin (mTOR) Pathway

Lin Chen, Guangsheng Yang, [...] Hongming Dong - Show fewer authors

DOI: 10.12659/MSM.912929

04 Sep 2019 : Laboratory Research

Overexpression of Biglycan is Associated with Resistance to Rapamycin in Human WERI-Rb-1 Retinoblastoma Cells by Inducing the Activation of the Phosphatidylinositol 3-Kinases (PI3K)/Akt/Nuclear Factor kappa B (NF-κB) Signaling Pathway

Dong Fang, Zhaoguang Lai, [...] Yan Wang - Show fewer authors

DOI: 10.12659/MSM.915075

20 Aug 2019 : Laboratory Research

SOX18 Affects Cell Viability, Migration, Invasiveness, and Apoptosis in Hepatocellular Carcinoma (HCC) Cells by Participating in Epithelial-to-Mesenchymal Transition (EMT) Progression and Adenosine Monophosphate Activated Protein Kinase (AMPK)/Mammalian Target of Rapamycin (mTOR)

Yanni Sun, Bo Lei, [...] Qingxian Huang - Show fewer authors

DOI: 10.12659/MSM.915729

08 Jun 2019 : Laboratory Research

Knockdown of Hypoxia-Inducible Factor 1α (HIF-1α) Promotes Autophagy and Inhibits Phosphatidylinositol 3-Kinase (PI3K)/AKT/Mammalian Target of Rapamycin (mTOR) Signaling Pathway in Ovarian Cancer Cells

Jinling Huang, Likun Gao, [...] Bingshu Li, Cheng Liu, Shasha Hong, Jie Min, Li Hong - Show fewer authors

DOI: 10.12659/MSM.915730

12 Nov 2019 : Laboratory Research

Eriocalyxin B Induces Apoptosis and Autophagy Involving Akt/Mammalian Target of Rapamycin (mTOR) Pathway in Prostate Cancer Cells

Ziqiang Yu, Yang Chen, [...] Chaozhao Liang - Show fewer authors

DOI: 10.12659/MSM.917333

21 Oct 2019 : Laboratory Research

Antiproliferative Activity of Carnosic Acid is Mediated via Inhibition of Cell Migration and Invasion, and Suppression of Phosphatidylinositol 3-Kinases (PI3K)/AKT/Mammalian Target of Rapamycin (mTOR) Signaling Pathway

Liqun Zhao, Juanni Zhang, [...] Yinke Fan, Ya Li - Show fewer authors

DOI: 10.12659/MSM.917735

27 Aug 2018 : Clinical Research

MicroRNA-495 Confers Increased Sensitivity to Chemotherapeutic Agents in Gastric Cancer via the Mammalian Target of Rapamycin (mTOR) Signaling Pathway by Interacting with Human Epidermal Growth Factor Receptor 2 (ERBB2)

Na Li, Mei Han, [...] Ning Zhou, Yong Tang, Xu-Shan Tang - Show fewer authors

DOI: 10.12659/MSM.909458