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21 October 2019 : Laboratory Research

Antiproliferative Activity of Carnosic Acid is Mediated via Inhibition of Cell Migration and Invasion, and Suppression of Phosphatidylinositol 3-Kinases (PI3K)/AKT/Mammalian Target of Rapamycin (mTOR) Signaling Pathway

DOI: 10.12659/MSM.917735

Med Sci Monit 2019; 25:7864-7871

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28 Apr 2020 : Animal Research

Apoptosis Activation in Thyroid Cancer Cells by Jatrorrhizine-Platinum(II) Complex via Downregulation of PI3K/AKT/Mammalian Target of Rapamycin (mTOR) Pathway

KeBin Lu, Wenjun Wei [...]

DOI: 10.12659/MSM.922518

Med Sci Monit 2020; 26:e922518

1886 22 16

21 Jul 2020 : Laboratory Research

Silencing of Long Non-Coding RNA (LncRNA) Non-Coding RNA Activated by DNA Damage (NORAD) Inhibits Proliferation, Invasion, Migration, and Promotes Apoptosis of Glioma Cells via Downregulating the Expression of AKR1B1

Lun Luo, Chuan Chen [...]

DOI: 10.12659/MSM.922659

Med Sci Monit 2020; 26:e922659

3367 13 144

28 Feb 2020 : Laboratory Research

Synaptotagmin 12 (SYT12) Gene Expression Promotes Cell Proliferation and Progression of Lung Adenocarcinoma and Involves the Phosphoinositide 3-Kinase (PI3K)/AKT/Mammalian Target of Rapamycin (mTOR) Pathway

Kaichao Liu, Jing Luo [...]

DOI: 10.12659/MSM.920351

Med Sci Monit 2020; 26:e920351

1998 26 33

02 Jan 2020 : Laboratory Research

S100A16 Regulates HeLa Cell through the Phosphatidylinositol 3 Kinase (PI3K)/AKT Signaling Pathway

Haibin Zhang, Yongxiu Yang [...]

DOI: 10.12659/MSM.919757

Med Sci Monit 2020; 26:e919757

1617 23 68

17 Mar 2019 : Laboratory Research

Murrayanine Induces Cell Cycle Arrest, Oxidative Stress, and Inhibition of Phosphorylated p38 Expression in A549 Lung Adenocarcinoma Cells

Jingbao Zhang, Yanfei Gao [...]

DOI: 10.12659/MSM.913873

Med Sci Monit 2019; 25:2002-2008

994 0 51

17 Feb 2019 : Laboratory Research

Phosphatase Actin Regulator-1 (PHACTR-1) Knockdown Suppresses Cell Proliferation and Migration and Promotes Cell Apoptosis in the bEnd.3 Mouse Brain Capillary Endothelial Cell Line

Yao Jing, Lin Zhang [...]

DOI: 10.12659/MSM.912586

Med Sci Monit 2019; 25:1291-1300

1642 26 98

01 Jan 2019 : Laboratory Research

Rho GTPase Activating Protein 24 (ARHGAP24) Silencing Promotes Lung Cancer Cell Migration and Invasion by Activating β-Catenin Signaling

Lei Wang, Saie Shen [...]

DOI: 10.12659/MSM.911503

Med Sci Monit 2019; 25:21-31

1416 14 40

03 Jan 2019 : Laboratory Research

Everolimus Reverses Palbociclib Resistance in ER+ Human Breast Cancer Cells by Inhibiting Phosphatidylinositol 3-Kinase(PI3K)/Akt/Mammalian Target of Rapamycin (mTOR) Pathway

Lin Chen, Guangsheng Yang [...]

DOI: 10.12659/MSM.912929

Med Sci Monit 2019; 25:77-86

1613 47 18

25 Mar 2019 : Clinical Research

Neuro-Protective Role of Metformin in Patients with Acute Stroke and Type 2 Diabetes Mellitus via AMPK/Mammalian Target of Rapamycin (mTOR) Signaling Pathway and Oxidative Stress

Min Zhao, Xiao Wan Li [...]

DOI: 10.12659/MSM.911250

Med Sci Monit 2019; 25:2186-2194

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08 Jun 2019 : Laboratory Research

Knockdown of Hypoxia-Inducible Factor 1α (HIF-1α) Promotes Autophagy and Inhibits Phosphatidylinositol 3-Kinase (PI3K)/AKT/Mammalian Target of Rapamycin (mTOR) Signaling Pathway in Ovarian Cancer Cells

Jinling Huang, Likun Gao [...]

DOI: 10.12659/MSM.915730

Med Sci Monit 2019; 25:4250-4263

1972 26 43

28 Aug 2019 : Animal Research

High-Mobility Group Box 1 (HMGB1) Induces Migration of Endothelial Progenitor Cell via Receptor for Advanced Glycation End-Products (RAGE)-Dependent PI3K/Akt/eNOS Signaling Pathway

Yulong Zhang, Bo You [...]

DOI: 10.12659/MSM.915829

Med Sci Monit 2019; 25:6462-6473

1636 24 25

05 Aug 2019 : Laboratory Research

Salidroside Suppresses IL-1β-Induced Apoptosis in Chondrocytes via Phosphatidylinositol 3-Kinases (PI3K)/Akt Signaling Inhibition

Mingzheng Wu, Rui Hu [...]

DOI: 10.12659/MSM.917851

Med Sci Monit 2019; 25:5833-5840

1539 36 23

08 Jul 2019 : Laboratory Research

Parthenolide Inhibits the Proliferation of MDA-T32 Papillary Thyroid Carcinoma Cells in Vitro and in Mouse Tumor Xenografts and Activates Autophagy and Apoptosis by Downregulation of the Mammalian Target of Rapamycin (mTOR)/PI3K/AKT Signaling Pathway

Chao Li, Yuqiu Zhou [...]

DOI: 10.12659/MSM.915387

Med Sci Monit 2019; 25:5054-5061

1473 1 39

02 Oct 2019 : Clinical Research

Tivantinib Hampers the Proliferation of Glioblastoma Cells via PI3K/Akt/Mammalian Target of Rapamycin (mTOR) Signaling

Yukun Wu, Zhizhang Li [...]

DOI: 10.12659/MSM.919319

Med Sci Monit 2019; 25:7383-7390

1344 16 26

19 Jun 2019 : Clinical Research

Proliferation of Ovarian Granulosa Cells in Polycystic Ovarian Syndrome Is Regulated by MicroRNA-24 by Targeting Wingless-Type Family Member 2B (WNT2B)

Zhong Yuanyuan, Wang Zeqin [...]

DOI: 10.12659/MSM.915320

Med Sci Monit 2019; 25:4553-4559

1477 28 27

16 Jun 2019 : Laboratory Research

Formiminotransferase Cyclodeaminase Suppresses Hepatocellular Carcinoma by Modulating Cell Apoptosis, DNA Damage, and Phosphatidylinositol 3-Kinases (PI3K)/Akt Signaling Pathway

Jiajia Chen, Zemian Chen [...]

DOI: 10.12659/MSM.916202

Med Sci Monit 2019; 25:4474-4484

1652 19 44

10 Jun 2019 : Laboratory Research

microRNA-378a Regulates the Reactive Oxygen Species (ROS)/Phosphatidylinositol 3-Kinases (PI3K)/AKT Signaling Pathway in Human Lens Epithelial Cells and Cataract

Yan Liu, Huanhuan Li [...]

DOI: 10.12659/MSM.916881

Med Sci Monit 2019; 25:4314-4321

1381 12 51

04 Jun 2019 : Animal Research

Loganin Attenuates Osteoarthritis in Rats by Inhibiting IL-1β-Induced Catabolism and Apoptosis in Chondrocytes Via Regulation of Phosphatidylinositol 3-Kinases (PI3K)/Akt

Yi Yang, Yuntao Gu [...]

DOI: 10.12659/MSM.915064

Med Sci Monit 2019; 25:4159-4168

1734 30 62

21 Nov 2018 : Laboratory Research

miR-339-5p Increases Radiosensitivity of Lung Cancer Cells by Targeting Phosphatases of Regenerating Liver-1 (PRL-1)

Jia Wang, Mawei Jiang [...]

DOI: 10.12659/MSM.910808

Med Sci Monit 2018; 24: LBR8408-8416

1330 8 24

07 Oct 2018 : Laboratory Research

Gambogic Acid Induces Apoptosis of Non-Small Cell Lung Cancer (NSCLC) Cells by Suppressing Notch Signaling

Minghua Zhu, Minjie Wang [...]

DOI: 10.12659/MSM.912563

Med Sci Monit 2018; 24: LBR7146-7151

1532 21 56

19 Sep 2018 : Animal Research

Protective Effects of Oleuropein Against Cerebral Ischemia/Reperfusion by Inhibiting Neuronal Apoptosis

Weijing Zhang, Xiaogang Liu [...]

DOI: 10.12659/MSM.912336

Med Sci Monit 2018; 24: ANS6587-6598

1387 12 14

09 Sep 2018 : Laboratory Research

Marsdenia Tenacissima Extract Inhibits Proliferation and Promotes Apoptosis in Human Ovarian Cancer Cells

Yuhong Zhang, Yangjia Zhang

DOI: 10.12659/MSM.909726

Med Sci Monit 2018; 24: LBR6289-6297

1806 60 52

16 Jul 2018 : Laboratory Research

The Effects of Ludartin on Cell Proliferation, Cell Migration, Cell Cycle Arrest and Apoptosis Are Associated with Upregulation of p21WAF1 in Saos-2 Osteosarcoma Cells In Vitro

Shuang-li Zhang, Bao-lin Li [...]

DOI: 10.12659/MSM.909193

Med Sci Monit 2018; 24: LBR4926-4933

1198 0 21

12 Jun 2018 : Laboratory Research

Role of Hydroxysteroid Dehydrogenase-Like 2 (HSDL2) in Human Ovarian Cancer

Qing Sun, Yilin Zhang [...]

DOI: 10.12659/MSM.909418

Med Sci Monit 2018; 24: LBR3997-4008

1410 8 78

10 Apr 2018 : Laboratory Research

Baicalin, a Chinese Herbal Medicine, Inhibits the Proliferation and Migration of Human Non-Small Cell Lung Carcinoma (NSCLC) Cells, A549 and H1299, by Activating the SIRT1/AMPK Signaling Pathway

Jiawen You, Jun Cheng [...]

DOI: 10.12659/MSM.909627

Med Sci Monit 2018; 24: LBR2126-2133

2323 27 54

18 Mar 2018 : Animal Research

Recombinant Osteopontin Improves Neurological Functional Recovery and Protects Against Apoptosis via PI3K/Akt/GSK-3β Pathway Following Intracerebral Hemorrhage

Wenqian Zhang, Ying Cui [...]

DOI: 10.12659/MSM.905700

Med Sci Monit 2018; 24: ANS1588-1596

1360 12 32

05 Feb 2018 : Laboratory Research

lncRNA BG981369 Inhibits Cell Proliferation, Migration, and Invasion, and Promotes Cell Apoptosis by SRY-Related High-Mobility Group Box 4 (SOX4) Signaling Pathway in Human Gastric Cancer

Xiuli Dong, Renpin Chen [...]

DOI: 10.12659/MSM.905965

Med Sci Monit 2018; 24: MOL718-726

1160 4 80

11 Feb 2018 : Laboratory Research

Ursolic Acid Attenuates High Glucose-Mediated Mesangial Cell Injury by Inhibiting the Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin (PI3K/Akt/mTOR) Signaling Pathway

Er-Min Wang, Qiu-Ling Fan [...]

DOI: 10.12659/MSM.907814

Med Sci Monit 2018; 24: LBR846-854

1473 6 14

31 Jan 2018 : Laboratory Research

Expression and Comparison of Cbl-b in Lung Squamous Cell Carcinoma and Adenocarcinoma

Peng Li, Hongliang Liu [...]

DOI: 10.12659/MSM.908076

Med Sci Monit 2018; 24: LBR623-635

1308 12 26

27 Aug 2018 : Clinical Research

MicroRNA-495 Confers Increased Sensitivity to Chemotherapeutic Agents in Gastric Cancer via the Mammalian Target of Rapamycin (mTOR) Signaling Pathway by Interacting with Human Epidermal Growth Factor Receptor 2 (ERBB2)

Na Li, Mei Han [...]

DOI: 10.12659/MSM.909458

Med Sci Monit 2018; 24: CLR5960-5972

1074 4 17

05 Sep 2018 : Laboratory Research

Calycosin, a Phytoestrogen Isoflavone, Induces Apoptosis of Estrogen Receptor-Positive MG-63 Osteosarcoma Cells via the Phosphatidylinositol 3-Kinase (PI3K)/AKT/Mammalian Target of Rapamycin (mTOR) Pathway

Haitao Sun, Mengfan Yin [...]

DOI: 10.12659/MSM.910201

Med Sci Monit 2018; 24: LBR6178-6186

1609 15 45

14 Feb 2017 : Animal Research

Evaluating the Effectiveness of GTM-1, Rapamycin, and Carbamazepine on Autophagy and Alzheimer Disease

Lijuan Zhang, Lina Wang [...]

DOI: 10.12659/MSM.898679

Med Sci Monit 2017; 23:801-808

2540 14 39

Editorial

01 April 2024 : Editorial  

Editorial: Forty Years of Waiting for Prevention and Cure of HIV Infection – Ongoing Challenges and Hopes for Vaccine Development and Overcoming Antiretroviral Drug Resistance

Dinah V. Parums

DOI: 10.12659/MSM.944600

Med Sci Monit 2024; 30:e944600

0:00

In Press

07 Mar 2024 : Clinical Research  

Knowledge of and Attitudes Toward Clinical Trials: A Questionnaire-Based Study of 179 Male Third- and Fourt...

Med Sci Monit In Press; DOI: 10.12659/MSM.943468  

0:00

08 Mar 2024 : Animal Research  

Modification of Experimental Model of Necrotizing Enterocolitis (NEC) in Rat Pups by Single Exposure to Hyp...

Med Sci Monit In Press; DOI: 10.12659/MSM.943443  

0:00

18 Apr 2024 : Clinical Research  

Comparative Analysis of Open and Closed Sphincterotomy for the Treatment of Chronic Anal Fissure: Safety an...

Med Sci Monit In Press; DOI: 10.12659/MSM.944127  

0:00

08 Mar 2024 : Laboratory Research  

Evaluation of Retentive Strength of 50 Endodontically-Treated Single-Rooted Mandibular Second Premolars Res...

Med Sci Monit In Press; DOI: 10.12659/MSM.944110  

Most Viewed Current Articles

17 Jan 2024 : Review article  

Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron Variant

DOI :10.12659/MSM.942799

Med Sci Monit 2024; 30:e942799

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14 Dec 2022 : Clinical Research  

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

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Med Sci Monit 2022; 28:e937990

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16 May 2023 : Clinical Research  

Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...

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01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

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Med Sci Monit 2022; 28:e935952

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750