07 May 2022>: Animal Study
Characterization of Inflammatory Factors and T Cell Subpopulations in a Murine Model of Kawasaki Disease Induced by Cell Wall Extracts (CAWS)
Huifang Xu ABG* , Jing Weng BCE , Quan Bao CE , Fengyan Nie D , Yuqiang Jiang E , Cong Xiao FDOI: 10.12659/MSM.936355
Med Sci Monit 2022; 28:e936355
Figure 1 The CAWS-induced murine model of KD with cardiac dysfunction, cardiac and vascular inflammation. (A) Fraction shortening, left ventricle end-diastolic diameter (LVEDD) and heart weight/body weight ratio were examined at 4 weeks after rhG-CSF treatment in CAWS-induced mice. **** p<0.0001. (B, C) The sections of hearts and arteries were stained at 4 weeks following rhG-CSF administration in CAWS-induced mice. Black arrow points to the indicated lesion location. Bar=50, 20 or 200 μm. GraphPad Prism software (version 8.0.1; Graph Pad; San Diego, CA, USA) and Olympus software (version 2.2; Olympus, Japan) were used to create the pictures.