Figure 3 Relationship between sleep, emotional state, and quality of life and inflammatory bowel disease. (A) Comparison of Patient Health Questionnaire scores between patients with good and poor sleep quality (4.33±4.19 versus 10.84±4.50; P<0.0001). (B) Comparison of Inflammatory Bowel Disease Questionnaire scores between patients with and without depression (153.94±28.95 versus 184.53±24.74). (C) Heat map of the correlation coefficients between Inflammatory Bowel Disease Questionnaire (IBDQ), Pittsburgh Sleep Quality Index (PSQI), Patient Health Questionnaire (PHQ-9) and Generalized Anxiety Disorder-7 (for each one coefficient: P<0.05). (D) Three-dimensional dispersion plot of patients with active disease (blue spots) and those in remission (red spots), based on PSQI, IBDQ, and PHQ-9 scores.