Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

21 January 2010

Alveolar soft part sarcoma metastasis to the choroid

Arkadiusz Pogrzebielski, Piotr Oleksy, Jolanta Orlowska-Heitzman, Bożena Romanowska-Dixon

Am J Case Rep 2010; 11:35-38 :: ID: 878335

Abstract

Background: Alveolar soft part sarcoma (ASPS) forms a rare group of sarcomas. ASPS is characterized by a relatively indolent clinical course, but the prognosis is eventually poor. In ophthalmic literature there is only a single case report on ASPS metastasis to the choroid. The aim of this report was to describe another patient with choroidal metastasis of ASPS.
Case Report: A 39-year-old woman was referred to the Clinic of Ophthalmology in Krakow, Poland. On examination in February 2009, a gray-yellow tumor located inferiorly in the left eye 6 mm from the edge of the optic disc was diagnosed. On B-scan ultrasound, the tumor base measured 14.7×15.6 mm and its apical thickness was 6.9–7.3 mm. MRI showed a tumor measuring 7×14×13 mm with elevated intensity on T1- and T2-weighted scans. In 1998 this patient had had surgical resection of a tumor in the left thigh. Histopathological examination revealed ASPS. In 2005, distant metastases to the lung were diagnosed and the patient underwent VAI chemotherapy. Because of poor response to chemotherapy, enucleation was recommended. The patient did not agree and I-125 brachytherapy was performed. Insufficient regression of the tumor associated with secondary exudative retinal detachment prompted the patient to decide to have the blind eye removed. The uneventful surgery took place in July 2009. Histopathology, PAS staining, and the immunohistochemical profile allowed us to diagnose ASPS metastasis to the choroid.
Conclusions: In very rare instances, the choroid may be the location of atypical metastases. ASPS metastasizes to the eye extremely rarely.

Keywords: alveolar soft-part sarcoma, intraocular tumor, Uvea, Choroid, metastasis

Add Comment 0 Comments

In Press

12 Feb 2024 : Case report  Germany

Diagnostic Challenges and Imaging Considerations for Intraparotid Facial Nerve Schwannoma: A Case Report an...

Am J Case Rep In Press; DOI: 10.12659/AJCR.942870  

0:00

12 Feb 2024 : Case report  USA

Erdheim-Chester Disease Occult on Radiographs and CT but Visible on MRI and PET

Am J Case Rep In Press; DOI: 10.12659/AJCR.941169  

0:00

12 Feb 2024 : Case report  USA

Surgical Treatment of Spontaneous Superficial Temporal Artery Arteriovenous Malformation: A Case Report

Am J Case Rep In Press; DOI: 10.12659/AJCR.942839  

13 Feb 2024 : Case report  Bahrain

Warfarin Woes: A Rare Case of Hemoperitoneum with Intramural Small Bowel Hematoma

Am J Case Rep In Press; DOI: 10.12659/AJCR.943519  

Most Viewed Current Articles

10 Jan 2022 : Case report  Germany

A Report on the First 7 Sequential Patients Treated Within the C-Reactive Protein Apheresis in COVID (CACOV...

DOI :10.12659/AJCR.935263

Am J Case Rep 2022; 23:e935263

19 Jul 2022 : Case report  Saudi Arabia

Atlantoaxial Subluxation Secondary to SARS-CoV-2 Infection: A Rare Orthopedic Complication from COVID-19

DOI :10.12659/AJCR.936128

Am J Case Rep 2022; 23:e936128

05 Mar 2022 : Case report  Brazil

Acute Limb Ischemia After Self-Injection of Crushed Morphine Tablets into the Radial Artery: Role of Infrar...

DOI :10.12659/AJCR.935336

Am J Case Rep 2022; 23:e935336

02 Apr 2022 : Case report  Saudi Arabia

Infective Endocarditis Caused by Pseudomonas luteola in a Pediatric Patient. A Case Report and Review of Li...

DOI :10.12659/AJCR.935743

Am J Case Rep 2022; 23:e935743

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923