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Medical Science Monitor Basic Research


eISSN: 1643-3750

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Primary Acute Angle-Closure Glaucoma: Three-Dimensional Reconstruction Imaging of Optic Nerve Heard Structure in Based on Optical Coherence Tomography (OCT)

Yi Wang, Di Chen, Wen Yang, Qianqian Cui, Weijie Hou, Wenhui Han, Xiaohua Huang, Wen Lu, Zilong Yuan, Jiumin Yuan, Yufang Teng, Jianfeng Qiu

(Department of Ophthalmology, Taishan Medical University, Taian, Shandong, China (mainland))

Med Sci Monit 2019; 25:3647-3654

DOI: 10.12659/MSM.913541

BACKGROUND: In glaucoma, the cup to plate ratio enlargement is a recognized pathological phenomenon. At present, the research on optic nerve in China and abroad mainly focuses on 2-dimensional research, and the measurement of 3-dimensional volume data is less well studied. Therefore, the recognition of 3-dimensional morphological changes is conducive to timely clinical intervention to prevent or slow down progressive vision loss.
MATERIAL AND METHODS: In this paper, optical coherence tomography (OCT) volume imaging technology was used to analyze and compare the morphological changes of primary acute angle-closure glaucoma in three-dimensional morphology, reconstruct the volume data of three-dimensional optic nerve head (ONH), and make morphological measurements.
RESULTS: The rim width of the glaucoma group was significantly lower than that of the control group, and the average volume and intraocular pressure of the optic cup were significantly increased (P<0.05), while the rim width and intraocular pressure of the other group were not significantly changed (P>0.05).
CONCLUSIONS: We used three-dimensional reconstruction to identify OCT images between glaucoma patients and the control group with significant differences.

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