18 July 2016 : Clinical Research
Evaluation of Transforaminal Endoscopic Discectomy in Treatment of Obese Patients with Lumbar Disc Herniation
Ya-peng WangE, Wei ZhangAFG, Ji-long AnB, Jian ZhangD, Jia-yue BaiC, Ya-peng SunGDOI: 10.12659/MSM.899510
Med Sci Monit 2016; 22:2513-2519
Abstract
BACKGROUND: This study aimed to evaluate the efficacy of transforaminal endoscopic discectomy (TED) in the treatment of obese patients with lumbar disc herniation (LDH).
MATERIAL AND METHODS: A total of 69 obese patients with LDH (35 males and 34 females; age range, 24 to 43 years; median age, 34 years) were included in this study. These patients had undergone TED from March 2011 to December 2015 in the Third Hospital of Hebei Medical University. Their clinical and follow-up data were prospectively analyzed. The degree of pain and disability were measured on the basis of the Visual Analog Scale (VAS) at 1 day before surgery, immediately after surgery, and 3 months after surgery. Neurologic functions were measured on the basis of the Japanese Orthopaedic Association (JOA) system 1 day before surgery and 3 months after surgery. The MacNab score at last follow-up was recorded to evaluate the early clinical efficacy. Complications during and after the operation were recorded to evaluate the safety of surgery.
RESULTS: Two patients experienced abnormal sensations in the export nerve root zone postoperatively, which disappeared after 3 days of treatment with dehydration and administration of hormone (dexamethasone). Three cases of recurrence were observed at 6 months, 7 months, and 9 months postoperatively; they were scheduled to receive total laminectomy combined with bone grafting internal fixation. A total of 67 patients were followed up for 3–23 months and mean follow-up was 11.8 months. The VAS scores at postoperative 3 months and 1 year were significantly reduced compared to that before the operation, with significant differences between them (t=43.072, P<0.05; t=43.139, P<0.05). The JOA scores at last follow-up postoperatively was significantly higher than that before surgery (t=–60.312, P<0.05). At the last follow-up, 17 cases (25.3%) had excellent outcomes, 39 (58.2%) good, 7 (10.4%) fair, and 4 (5.9%) poor. Overall, 83.5% of patients had excellent or good rates.
CONCLUSIONS: The early efficacy of TED is relatively good and safe for the selected obese patients with LDH in this study. Larger-sample studies with longer duration and follow-up are required to detect the safety and effectiveness of TED.
Keywords: Diskectomy, Percutaneous, Osteoarthritis, Spine
Editorial
01 July 2026 : Editorial
Editorial: The WHO Identifies Ebola Disease Due to Bundibugyo Virus as a Public Health Emergency of International Concern (PHEIC) as Vaccine Development AcceleratesDOI: 10.12659/MSM.954627
Med Sci Monit 2026; 32:e954627
In Press
Review article
Clinical Use of Endotracheal Intubation Without Neuromuscular Blockade: The Current Stage of KnowledgeMed Sci Monit In Press; DOI: 10.12659/MSM.951765
Clinical Research
Effect of Dexmedetomidine Hydrochloride Nasal Spray on Anxiety and Sleep in Patients Undergoing Gynecologic...Med Sci Monit In Press; DOI: 10.12659/MSM.952465
Clinical Research
Prognostic Value of Mortality Scoring Systems in Patients With Severe Burns: Identifying Key Predictors of ...Med Sci Monit In Press; DOI: 10.12659/MSM.951713
Laboratory Research
Evaluation of the Trueness and Precision of Cast, Milled-Cast, Milled, and 3D-Printed Post-and-Core Techniq...Med Sci Monit In Press; DOI: 10.12659/MSM.953491
Most Viewed Current Articles
17 Jan 2024 : Review article 14,176,214
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
13 Nov 2021 : Clinical Research 3,757,839
Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...DOI :10.12659/MSM.932788
Med Sci Monit 2021; 27:e932788
14 Dec 2022 : Clinical Research 2,466,153
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
16 May 2023 : Clinical Research 708,809
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387






