H-Index
79
Scimago Lab
powered by Scopus
JCR
Clarivate
Analytics
12%
Acceptance
Rate
call: +1.631.470.9640
Mon-Fri 10 am - 2 pm EST

Logo

Medical Science Monitor Basic Research
AmJCaseRep

Annals
ISI-Home

eISSN: 1643-3750

Get your full text copy in PDF

Incidence of new cardiovascular events in patients with and without peripheral arterial disease seen in a vascular surgery clinic

Amit Chhabra, Wilbert S. Aronow, Chul Ahn, Kurt Duncan, Jay D. Patel, Alexander I. Papolos, Babu Sateesh

Med Sci Monit 2012; 18(3): CR131-134

DOI: 10.12659/MSM.882517


Background:    To investigate the incidence of death and of new cardiovascular events at long-term follow-up of patients with and without PAD seen in a vascular surgery clinic.
    Material/Methods:    We investigated the incidence of death, new stroke/transient ischemic attack, new myocardial infarction, new coronary revascularization, new carotid endarterectomy, new peripheral arterial disease (PAD) revascularization, or at least one of the above outcomes at long-term follow-up of patients with and without PAD followed in a vascular surgery clinic.
    Results:    At least one of the above outcomes occurred in 259 of 414 patients (63%) with PAD at 33-month follow-up and in 21 of 89 patients (24%) without PAD at 48-month follow-up (p<0.0001). Death occurred in 112 of 414 patients (27%) with PAD and in 10 of 89 patients (11%) without PAD (p=0.002). Stepwise Cox regression analysis for the time to at least one of the 6 outcomes showed that significant independent risk factors were men (hazard ratio =1.394; 95% CI, 1.072–1.813; p=0.013), estimated glomerular filtration rate (hazard ratio =0.992; 95% CI, 0.987–0.997; p=0.003), and PAD (hazard ratio =3.520; 95% CI, 2.196–5.641; p<0.0001). Stepwise Cox regression analysis for the time to death showed that significant independent risk factors were age (hazard ratio =1.024; 95% CI, 1.000–1.049; p=0.048), estimated glomerular filtration rate (hazard ratio =0.985; 95% CI, 0.974–0.996; p=0.007), and PAD (hazard ratio =2.157; 95% CI, 1.118–4.160; p=0.022).
    Conclusions:    Patients with PAD have a significantly higher incidence of cardiovascular outcomes, especially death, new PAD revascularization, and new carotid endarterectomy, than patients without PAD followed in a vascular surgery clinic.

This paper has been published under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) allowing to download articles and share them with others as long as they credit the authors and the publisher, but without permission to change them in any way or use them commercially.
I agree