Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

01 December 2008

Renal function with left ventricular assist devices: the poorer the preoperative renal function, the longer the recovery

Ling MaABCDEF, Yuji FujinoABCDEFG, Goro MatsumiyaF, Yoshiki SawaF, Takashi MashimoG

Med Sci Monit 2008; 14(12): CR621-627 :: ID: 869484

Abstract

Background
After left ventricular assist device (LVAD) implantation, post-operative renal failure is a fairly high risk. While comparing the differences in indicators of renal function associated with the use of three different types of LVAD, this retrospective study was designed to evaluate predictors and outcomes of acute renal failure after LVAD insertion.
Material and Method
Data for 28 patients who had received left ventricular assist device (LVAD) implantation at Osaka University Hospital from January 2002 through February 2007 were retrospectively analyzed. We correlated preoperative creatinine levels with the number of days needed for the creatinine level to drop below 1.5 mg/dL. Using the preoperative serum creatinine level as a univariate risk predictor, receiver operating characteristic (ROC) curves were analyzed to determine the best cutoff points for predicting ICU stays more than 30 days. Patients were characterized according to the type of LVAD pump implanted, their hemodynamic data, and other laboratory test data that were collected and analyzed.
Results
In our population, the type of LVAD was not related to the number of days needed for creatinine to drop to 1.5 mg/dL. Preoperative serum creatinine, however, did correlate with prolonged high postoperative creatinine levels: ROC analysis shows that a preoperative creatinine level of more than 1.95 mg/dL predicts an ICU stay more than 30 days. Ten patients implanted with Toyobo LVADs had preoperative creatinine levels above 1.5 mg/dL. The Pearson's correlation of their body weight and their final creatinine level when transferred from the ICU was 0.758 (P=0.011).
Conclusions
Preoperative renal function predicts post-implantation renal function and length of ICU stay. Especially when implanted in heavier patients, the Toyobo LVAD tends to provide poorer renal perfusion.

Keywords: Length of Stay, Preoperative Care, Kidney Function Tests, Intensive Care Units, Heart-Assist Devices, Creatinine - blood

Add Comment 0 Comments

Editorial

01 March 2024 : Editorial  

Editorial: First Regulatory Approvals for CRISPR-Cas9 Therapeutic Gene Editing for Sickle Cell Disease and Transfusion-Dependent β-Thalassemia

Dinah V. Parums

DOI: 10.12659/MSM.944204

Med Sci Monit 2024; 30:e944204

0:00

In Press

18 Mar 2024 : Clinical Research  

Sexual Dysfunction in Women After Tibial Fracture: A Retrospective Comparative Study

Med Sci Monit In Press; DOI: 10.12659/MSM.944136  

0:00

21 Feb 2024 : Clinical Research  

Potential Value of HSP90α in Prognosis of Triple-Negative Breast Cancer

Med Sci Monit In Press; DOI: 10.12659/MSM.943049  

22 Feb 2024 : Review article  

Differentiation of Native Vertebral Osteomyelitis: A Comprehensive Review of Imaging Techniques and Future ...

Med Sci Monit In Press; DOI: 10.12659/MSM.943168  

23 Feb 2024 : Clinical Research  

A Study of 60 Patients with Low Back Pain to Compare Outcomes Following Magnetotherapy, Ultrasound, Laser, ...

Med Sci Monit In Press; DOI: 10.12659/MSM.943732  

Most Viewed Current Articles

16 May 2023 : Clinical Research  

Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...

DOI :10.12659/MSM.940387

Med Sci Monit 2023; 29:e940387

0:00

17 Jan 2024 : Review article  

Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron Variant

DOI :10.12659/MSM.942799

Med Sci Monit 2024; 30:e942799

0:00

14 Dec 2022 : Clinical Research  

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990

0:00

01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

0:00

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750