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Effect of splenectomy on the morphology of haemolymph splenic nodes in Wistar rats

Konstanty ƚlusarczyk, Beata Marniok, Piotr Rudnicki

Med Sci Monit 2000; 6(4): BR675-679

ID: 508125

Material/Methods:     In 12 Wistar rats the gross and microscopic structure of haemolymph splenic nodes was assessed after splenectomy and the obtained results were compared with those in the control group.
Results:     It was found that splenectomy leads to generalised morphological changes of the mentioned nodes, including, among other, their blanching, enlargement, filling with a greater number of morphotic elements and decreased count of erythrocytes and products of their disintegration. The splenic nodes demonstrated no regressive changes, typical of uniorgan nodes. The remaining abdominal non-haemolymph nodes in the rats showed no compensatory changes on gross examination after splenectomy.

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