Scimago Lab
powered by Scopus
call: +1.631.470.9640
Mon-Fri 10 am - 2 pm EST


Medical Science Monitor Basic Research


eISSN: 1643-3750

Get your full text copy in PDF

Comparative studies of serum and salivary estriol concentrations in third trimester of normal pregnancy

Beata Kos-Kudła, Piotr Skałba, Marek Kudła, Bogdan Marek, Zofia Ostrowska, Barbara Buntner

Med Sci Monit 1999; 5(2): CR285-288

ID: 505135

The measurement of serum estriol (E3) level, monitoring the function of fetoplacental unit, is an important parameter in human pregnancy. 62 healthy women aged 20-37 (mean age 27.1±4.6 years) in third trimester of normal pregnancy were included in the study, and divided into six groups depending on the time of pregnancy. The aim of the present work was to evaluate fetus well-being with use of non-invasive method of free estriol determination in saliva of women in third trimester of normal pregnancy (elaboration of own norms) as well as to determine the correlation between serum and salivary estriol concentrations. Salivary and serum estriol concentrations were determined in all studied women. Saliva and blood were collected between 8 a.m. and 9 a.m. Non-conjugated estriol concentration in serum (uE3) and in saliva (SE3) were measured with radioimmunoassay. There was a significant correlation (r=0.76, p < 0.001) between estriol concentrations in serum and saliva. Percentage proportion of salivary estriol to serum estriol concentration fluctuated between 6.51-9.5%. Normal range of salivary estriol concentration for particular weeks of third trimester of normal human pregnancy was presented.

This paper has been published under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) allowing to download articles and share them with others as long as they credit the authors and the publisher, but without permission to change them in any way or use them commercially.
I agree