H-Index
79
Scimago Lab
powered by Scopus
JCR
Clarivate
Analytics
15%
Acceptance
Rate
call: +1.631.470.9640
Mon-Fri 10 am - 2 pm EST

Logo

Medical Science Monitor Basic Research
AmJCaseRep

Annals
ISI-Home

eISSN: 1643-3750

Get your full text copy in PDF

Soluble HLA class I antigens (s-HLA-I) in osteporotic patients sera

Gabriel Turowski, Anna Kędzierska, Danuta Gieracka-Pażucha, Joanna Flasza, Lidia Rutowicz

Med Sci Monit 1997; 3(3): CR373-377

ID: 501141


In the sera of 20 patients with radiographically diagnosed 3rd degree osteoporosis (type I-post menopausal, type II-of elderly age) concentrations of soluble HLA-class I antigens were determined. In these patients, HLA-ABC phenotypes were first identified, then levels of sHLA-I were determined in a semiquantitative test of lymphocytotoxic reaction inhibition according to Tait et al. and McLean et al. with our modification. Varying sHLA-I concentrations were obtained for the majority of examined HLA specificities encoded by HLA-A, B and C loci in these patients. The results were compared with similar measurements in a control population of 205 healthy unrelated adults. A statistically significant difference was shown for HLA-B27 and HLA-B44 .

This paper has been published under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) allowing to download articles and share them with others as long as they credit the authors and the publisher, but without permission to change them in any way or use them commercially.
I agree