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Medical Science Monitor Basic Research


eISSN: 1643-3750

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An attempt to estimate the results of the treatment of gastritis coexistent with helicobacter pylori infection in children

Maria Korzon, Wiesława Bukowska, Barbara Kamińska, Piotr Banach, Wojciech Radys

Med Sci Monit 1997; 3(3): CR342-345

ID: 501088

This study presents 44 cases of gastritis and/or duodenitis coexistent with Helicobacter pylori colonization in children. The diagnosis was established on the basis of endoscopy examination of gastric and/or duodenal mucosa, histopathological examination of the mucosa, CLO-test and bacteriologic culture. A group of 37 children were treated with triple therapy (DE-NOL, Amoxicillin and Metronidazole), 7 patients received Omeprazol. Eradication of H. pylori and regression of symptoms was observed in 20 and 7 cases, respectively. Ascertaining the effects of treatment in all cases was not possible; we were unable to obtain patients' consent for a follow-up endoscopy for some children, mainly among those patients in whom treatment led to the regression of symptoms. Reliable, non-invasive tests for the detection of H. pylori infections are needed to fully evaluate therapy for this problem.

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