01 December 2006
Memory and perceptuo-motor performance in Nigerians with chronic renal impairment
A. Olubunmi Ogunrin, Evelyn I. Unuigbe, Chuks AzubuikeMed Sci Monit 2006; 12(12): CR535-539 :: ID: 469556
Abstract
Background: With the increasing prevalence of chronic renal failure among the indigenous African population, coupled with the emphasis on improvement in the quality of life, there is a need for reports on the cognitive functioning and the effect of the disease on the cognitive performance of affected individuals.
Material/Methods: Sixty consecutive non-dialyzed Nigerian patients with clinical and biochemical evidence of chronic renal failure and sixty healthy age-, sex- and education level-matched controls (volunteers) were studied using an automated neuro-psychological test battery (FePsy) to assess their memory and perceptuo-motor skills.
Results: The chronic renal failure patients performed worse in both verbal and visual memory than controls (p0.05), but their perceptuo-motor speed was retarded (p<0.001). The levels of creatinine (p<0.01) and urea (p<0.01) and the presence of hypertension (p<0.05), asterixis (p<0.05), exertional dyspnea (p<0.05), and vomiting (p<0.05) affected their memory performance, with creatinine level being the most potent variable (p=0.0015).
Conclusions: The results of this study confirm the presence of cognitive impairments in Nigerians with chronic renal impairment and buttress the importance of its aggressive and prompt management.
Keywords: Case-Control Studies, Kidney Failure, Chronic - psychology, Memory Disorders - psychology, Nigeria, Psychomotor Performance
Editorial
01 April 2024 : Editorial
Editorial: Forty Years of Waiting for Prevention and Cure of HIV Infection – Ongoing Challenges and Hopes for Vaccine Development and Overcoming Antiretroviral Drug ResistanceDOI: 10.12659/MSM.944600
Med Sci Monit 2024; 30:e944600
In Press
08 Mar 2024 : Clinical Research
Evaluation of Foot Structure in Preschool Children Based on Body MassMed Sci Monit In Press; DOI: 10.12659/MSM.943765
15 Apr 2024 : Laboratory Research
The Role of Copper-Induced M2 Macrophage Polarization in Protecting Cartilage Matrix in OsteoarthritisMed Sci Monit In Press; DOI: 10.12659/MSM.943738
07 Mar 2024 : Clinical Research
Knowledge of and Attitudes Toward Clinical Trials: A Questionnaire-Based Study of 179 Male Third- and Fourt...Med Sci Monit In Press; DOI: 10.12659/MSM.943468
08 Mar 2024 : Animal Research
Modification of Experimental Model of Necrotizing Enterocolitis (NEC) in Rat Pups by Single Exposure to Hyp...Med Sci Monit In Press; DOI: 10.12659/MSM.943443
Most Viewed Current Articles
17 Jan 2024 : Review article
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
14 Dec 2022 : Clinical Research
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
16 May 2023 : Clinical Research
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952