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eISSN: 1643-3750

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Possible association between circulating vascular endothelial growth factor and oxidative stress markers in hemodialysis patients.

Krystyna Pawlak, Dariusz Pawlak, Michał Myśliwiec

Med Sci Monit 2006; 12(4): CR181-186

ID: 448909


Background: Vascular endothelial growth factor is involved in the processof atherogenesis. Increased oxidative stress has been reported in hemodialyzed patients, but its influenceon vascular endothelial growth factor levels remains unknown. Material/Methods: The levels of two oxidativestress markers, Cu/Zn superoxide dismutase and autoantibodies against oxidized LDL, and the level ofvascular endothelial growth factor were measured in pre-dialysis samples of hemodialyzed patients withand without cardiovascular disease and in healthy controls. Results: Vascular endothelial growth factorlevels were significantly increased in both hemodialysis groups compared with controls (all p

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