01 March 2006
Chronic black tea administration protects plasma proteins, plasma, liver andkidney lipids against oxidation.
Esma Sürmen-Gür, Tuna Gülten, Zehra Serdar, Mukaddes ColakogullariMed Sci Monit 2006; 12(3): BR102-105 :: ID: 447103
Abstract
Background: Black tea is known to have protective effects against plasmalipid and lipoprotein oxidation, but its influence on lipid peroxidation in tissue has been less studied.The effect of oral black tea consumption on protein oxidation has also not been demonstrated. The presentstudy investigated the antioxidant effects of oral black tea consumption. Material/Methods: Male Sprague-Dawleyrats were fed a regular murine chow diet. The controls were supplied with water ad libitum, while theblack tea group received aqueous black tea extract as the sole source of liquids. At the end of the ten-weekexperimental period, intestinal brush border, liver and kidney reduced-glutathione concentrations wereevaluated as an index of cellular antioxidant defence. Plasma and tissue malondialdehyde concentrationsand plasma protein carbonyl content were measured to evaluate lipid peroxidation and protein oxidation,respectively. Results: The plasma malondialdehyde and protein carbonyl contents of rats consuming theblack tea were significantly less than in controls. Similarly, liver and kidney malondialdehyde concentrationswere significantly lower in the experimental group, while jejunoileal mucosa were not affected. Ten weeksof black tea administration caused significantly higher reduced-glutathione levels in the kidneys ofblack tea-administered rats, and a significant negative correlation was observed between kidney malondialdehydeand glutathione concentrations. Conclusions: These findings provide evidence that long term black teasupplementation is capable of protecting both plasma proteins and plasma lipids from oxidative injury,and demonstrate that chronic black tea administration protects both liver and kidney tissues - but notthe jejunoileal mucosa - against oxidation.
Keywords: Thiobarbituric Acid Reactive Substances - analysis, Tea - chemistry, Reference Standards, Random Allocation, Plant Extracts - pharmacology, Malondialdehyde - blood, Antioxidants - pharmacology, Liver - drug effects, Lipids - blood, Lipid Peroxidation - drug effects, Kidney - drug effects, Glutathione - analysis, Blood Proteins - drug effects, Administration, Oral
Editorial
01 April 2024 : Editorial
Editorial: Forty Years of Waiting for Prevention and Cure of HIV Infection – Ongoing Challenges and Hopes for Vaccine Development and Overcoming Antiretroviral Drug ResistanceDOI: 10.12659/MSM.944600
Med Sci Monit 2024; 30:e944600
In Press
21 Mar 2024 : Meta-Analysis
Economic Evaluation of COVID-19 Screening Tests and Surveillance Strategies in Low-Income, Middle-Income, a...Med Sci Monit In Press; DOI: 10.12659/MSM.943863
10 Apr 2024 : Clinical Research
Predicting Acute Cardiovascular Complications in COVID-19: Insights from a Specialized Cardiac Referral Dep...Med Sci Monit In Press; DOI: 10.12659/MSM.942612
06 Mar 2024 : Clinical Research
Enhanced Surgical Outcomes of Popliteal Cyst Excision: A Retrospective Study Comparing Arthroscopic Debride...Med Sci Monit In Press; DOI: 10.12659/MSM.941102
06 Mar 2024 : Clinical Research
Prevalence and Variation of Medical Comorbidities in Oral Surgery Patients: A Retrospective Study at Jazan ...Med Sci Monit In Press; DOI: 10.12659/MSM.943884
Most Viewed Current Articles
17 Jan 2024 : Review article
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
14 Dec 2022 : Clinical Research
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
16 May 2023 : Clinical Research
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952