01 September 2003
Treatment outcome for osteosarcoma in children. The experience of single institution
Stefan Popadiuk, Małgorzata Szumera, Jacek Gołębiewski, Katarzyna Sznurkowska, Maria KorzonMed Sci Monit 2003; 9(4): 38-40 :: ID: 428633
Abstract
Background: Osteosarcoma is the most frequent primary bone malignancy in children. Preoperative and postoperative chemotherapy and radical surgery are used in treatment of osteosarcoma.Material/Methods: In the years 1995 –1999 twenty patients with osteosarcoma were treated. All children were given preoperative chemotherapy, then radical resection of primary tumor and finally postoperative chemotherapy was introduced. Nineteen of twenty patients received two drugs chemotherapy: adriamycin /cisplatin.A median follow-up is 6.2 years.Results: Disease Free Survival (DFS) and Event Free Survival (EFS) for all the group were 0.7 and 0.45, and for non-metastatic patients DFS and EFS were 0.78 and 0.50 respectively. In 55 %of patients limb–sparing surgery was performed, the others under-went amputation. No severe, late toxic effects were observed after the treatment.Conclusions: The results confirmed the efficacy of EOI protocol in pediatric patients with osteosarcoma. A relatively large number of secondary mtetastases after completion of therapy is still unsatisfactory.
Keywords: children, treatment
Editorial
01 March 2024 : Editorial
Editorial: First Regulatory Approvals for CRISPR-Cas9 Therapeutic Gene Editing for Sickle Cell Disease and Transfusion-Dependent β-ThalassemiaDOI: 10.12659/MSM.944204
Med Sci Monit 2024; 30:e944204
In Press
18 Mar 2024 : Clinical Research
Sexual Dysfunction in Women After Tibial Fracture: A Retrospective Comparative StudyMed Sci Monit In Press; DOI: 10.12659/MSM.944136
21 Feb 2024 : Clinical Research
Potential Value of HSP90α in Prognosis of Triple-Negative Breast CancerMed Sci Monit In Press; DOI: 10.12659/MSM.943049
22 Feb 2024 : Review article
Differentiation of Native Vertebral Osteomyelitis: A Comprehensive Review of Imaging Techniques and Future ...Med Sci Monit In Press; DOI: 10.12659/MSM.943168
23 Feb 2024 : Clinical Research
A Study of 60 Patients with Low Back Pain to Compare Outcomes Following Magnetotherapy, Ultrasound, Laser, ...Med Sci Monit In Press; DOI: 10.12659/MSM.943732
Most Viewed Current Articles
16 May 2023 : Clinical Research
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
17 Jan 2024 : Review article
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
14 Dec 2022 : Clinical Research
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952