01 September 2005
Dyspeptic complaints after 20 weeks of gestation are not related to Helicobacter pylori seropositivity
Hamit Alper Tanriverdi, Yucel Ustundag, Ishak Ozer Tekin, Aykut BarutMed Sci Monit 2005; 11(9): CR445-448 :: ID: 428454
Abstract
Background: This study was to test whether an association exists betweenHelicobacter pylori seropositivity and severity of dyspeptic symptoms after 20 weeks of gestation inpregnant women. Material/Methods: Pregnant women (n=103) with gestational ages between 20-41 weeks andhealthy non-pregnant women (controls, n=79) were prospectively enrolled in the study. Anti-H. PyloriIgG serum antibody was tested to establish seropositivity. The dyspeptic symptoms were evaluated by theGlasgow Dyspepsia Severity Score in the pregnant group and classified as asymptomatic (score 0), mildlysymptomatic (score 1-5), and severely symptomatic (score 6). The severity of dyspeptic symptoms was comparedin pregnant women with H. Pylori seropositivity, and pregnant and non-pregnant women were compared forH. Pylori seropositivity and prevalence of dyspeptic symptoms. The results were analyzed using Student'st, Mann-Whitney-U, and chi-square tests. Results: The prevalence of H. Pylori seropositivity was notdifferent among pregnant and non-pregnant women. The median dyspeptic scores were 5 and 4, respectively,for H. Pylori seropositive and negative pregnant women. Dyspeptic scores of H. Pylori seropositive pregnantwomen were not different from those of uninfected pregnant women. H. Pylori seropositivity did not differamong asymptomatic and mildly and severely symptomatic pregnant women. The non-pregnant women were moreoften asymptomatic than pregnant women. Conclusions: Our findings do not support any association betweenH. Pylori seropositivity and severity of dyspeptic symptoms in late pregnancy. It seems unreasonableto screen women in late pregnancy for H. Pylori seropositivity, even if they suffer from severe dyspepticsymptoms.
Keywords: Adolescent, Antibodies, Bacterial - blood, Case-Control Studies, Dyspepsia - microbiology, Helicobacter Infections - immunology, Helicobacter pylori - immunology, Pregnancy, Pregnancy Complications, Infectious - microbiology, Prospective Studies
Editorial
01 March 2024 : Editorial
Editorial: First Regulatory Approvals for CRISPR-Cas9 Therapeutic Gene Editing for Sickle Cell Disease and Transfusion-Dependent β-ThalassemiaDOI: 10.12659/MSM.944204
Med Sci Monit 2024; 30:e944204
In Press
21 Feb 2024 : Clinical Research
Potential Value of HSP90α in Prognosis of Triple-Negative Breast CancerMed Sci Monit In Press; DOI: 10.12659/MSM.943049
22 Feb 2024 : Review article
Differentiation of Native Vertebral Osteomyelitis: A Comprehensive Review of Imaging Techniques and Future ...Med Sci Monit In Press; DOI: 10.12659/MSM.943168
23 Feb 2024 : Clinical Research
A Study of 60 Patients with Low Back Pain to Compare Outcomes Following Magnetotherapy, Ultrasound, Laser, ...Med Sci Monit In Press; DOI: 10.12659/MSM.943732
26 Feb 2024 : Clinical Research
Predictive Value of Combined HbA1c and Neutrophil-to-Lymphocyte Ratio for Diabetic Peripheral Neuropathy in...Med Sci Monit In Press; DOI: 10.12659/MSM.942509
Most Viewed Current Articles
17 Jan 2024 : Review article
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
16 May 2023 : Clinical Research
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
14 Dec 2022 : Clinical Research
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952