H-Index
79
Scimago Lab
powered by Scopus
JCR
Clarivate
Analytics
15%
Acceptance
Rate
call: +1.631.470.9640
Mon-Fri 10 am - 2 pm EST

Logo



eISSN: 1643-3750

Get your full text copy in PDF

Prevalence of Anticardiolipin Antibody IgG in Recurrent First Trimester Abortions and the Role of Aspirin in Its Prevention

Sunita Kalra, Anita Tuli, Rewa Choudhry, Shashi Raheja

Med Sci Monit 2003; 9(6): CR213-216

ID: 12712


Background:Approximately 10% of all human pregnancies end in spontaneous abortions. In the majority of such cases the etiology remains unknown, but anticardiolipin antibodies are gaining recognition as potential causes of recurrent miscarriage.Material/Methods:The prevalence of anticardiolipin antibody IgG (IgGacl) in 60 pregnant patients with recurrent first trimester abortions and 60 pregnant controls of comparable age with no history of abortion were examined to find a possible relation between IgGacl and spontaneous abortion. The assay for IgGacl was done by Enzyme Linked Immunosorbent Assay (ELISA). Positive test results were considered ‘strongly elevated’ with IgGacl levels exceeding 36 GPL units. Aspirin (80 mg per day) was prescribed for patients with recurrent first trimester abortion and strongly elevated levels of IgGacl.Results:Strongly elevated levels of IgGacl were detected in a total of 18 patients (30%) with recurrent abortions, and none of the controls (p

This paper has been published under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) allowing to download articles and share them with others as long as they credit the authors and the publisher, but without permission to change them in any way or use them commercially.
I agree