05 May 2022>: Clinical Research
Predictive Value of Procalcitonin and Neutrophil-to-Lymphocyte Ratio Variations for Bloodstream Infection with Septic Shock
Peipei Liang ABCDEFG , Feng Yu AFG*DOI: 10.12659/MSM.935966
Med Sci Monit 2022; 28:e935966
Table 4 Performance of variables in predicting septic shock in patients with bloodstream infection.
Test variables | AUC (95%CI) | P value | Specificity (%) | Sensitivity (%) |
---|---|---|---|---|
PCT0h | 0.743 (0.661, 0.826) | 78.00 | 70.50 | |
NLR0h | 0.756 (0.686, 0.825) | 92.13 | 38.36 | |
PCT48h | 0.769 (0.702, 0.836) | 94.08 | 32.23 | |
NLR48h | 0.682 (0.606, 0.758) | 81.25 | 41.09 | |
ΔPCT | 0.834 (0.778, 0.891) | 75.03 | 80.98 | |
ΔNLR | 0.852 (0.797, 0.908) | 76.98 | 83.82 | |
ΔPCT+ΔNLR | 0.937 (0.905, 0.970) | 92.80 | 80.02 | |
AUC – area under curve; NLR – neutrophil-to-lymphocyte ratio; PCT – procalcitonin; NLR0h – NLR at 0 hours; NLR48h – NLR at 48 hours; PCT0h – PCT at 0 hours; PCT48h – PCT at 48 hours. |