03 June 2022>: Clinical Research
Early Enteral Nutrition Can Reduce Incidence of Postoperative Hydrocephalus in Patients with Severe Hypertensive Intracerebral Hemorrhage
Zhi Cai BCE , Kai Zhao AEG , Yu Li BC , Xueyan Wan B , Chunlin Li B , Hongquan Niu DF , Kai Shu DF , Ting Lei A*DOI: 10.12659/MSM.935850
Med Sci Monit 2022; 28:e935850
Table 1 The clinical characteristics of 146 patients with severe HICH.
Variables | Values |
---|---|
Age, years (SD) | 51.7 (11.4) |
Gender (%) | |
Male | 87 (59.6) |
Female | 59 (40.4) |
Nutritional status at admission | |
BMI, kg/m (SD) | 24.1 (3.5) |
Mid-arm muscle circumference, cm (SD) | 30.1 (4.5) |
Albumin, g/L (M (P, P)) | 42.4 (39.3, 47.4) |
SGA (%) | |
Well-nourished | 9 (6.2) |
Moderately malnourished | 99 (67.8) |
Severely malnourished | 38 (26.0) |
Hematoma location (%) | |
Lobes | 36 (24.6) |
Basal ganglia | 81 (55.5) |
Thalamus | 15 (10.3) |
Cerebellum | 14 (9.6) |
Volume of hematoma, ml (SD) | 49.5 (23.6) |
SAH (%) | 25 (17.1) |
IVH (%) | 84 (57.5) |
Preoperative GCS (M (P2, P)) | 6.2 (5,8) |
Surgical treatment (%) | |
Hematoma removal | 103 (70.5) |
DC | 28 (15.0) |
EVD | 45 (34.9) |
EN application (%) | |
Early EN | 51 (34.9) |
Delayed EN | 95 (65.1) |
Supported PN administration (%) | 87 (59.6) |
Hydrocephalus (%) | |
Acute | 27 (18.5) |
Chronic | 20 (13.7) |
Postoperative GCS (M (P, P)) | 10.4 (7,14) |
mRS (SD) | 4.2 (0.4) |
Nutritional status at two weeks postoperatively | |
BMI, kg/m (SD) | 23.0 (3.0) |
Mid-arm muscle circumference, cm (SD) | 28.6 (3.9) |
Albumin, g/L (SD) | 33.6 (4.9) |
SGA (%) | |
Well-nourished | 17 (11.6) |
Moderately malnourished | 101 (69.2) |
Severely malnourished | 28 (19.2) |
Laboratory results | |
White blood cells, 10 (M (P, P)) | 14.3 (10.5, 17.5) |
Neutrophil, 10 (M (P, P)) | 12.0 (8.4, 15.0) |
Lymphocyte, 10 (M (P, P)) | 1.2 (0.9, 1.4) |
Monocyte, 10 (M (P, P)) | 1.2 (0.8, 1.5) |
Platelet, 10 (M (P, P)) | 265.4 (174.3, 344.3) |
NLR (M (P, P)) | 11.2 (7.1, 13.8) |
dNLR (M (P, P)) | 2.0 (1.7, 2.2) |
MLR (M (P, P)) | 1.0 (0.7, 1.2) |
PLR (M (P, P)) | 236.8 (166.4, 280.3) |
CRP, mg/L (M (P, P)) | 41.6 (10.7, 61.7) |
LDH, U/L (M (P, P)) | 286.1 (213.8, 360.0) |
BMI – body mass index; CRP – C-reactive protein; DC – decompression craniectomy; dNLR – derived NLR; EN – enteral nutrition; EVD – extraventricular drainage; GCS – Glasgow coma scale; IVH – intraventricular hemorrhage; LDH – lactate dehydrogenase; MLR – monocyte-to-lymphocyte ratio; mRS – Modified Rankin Scale; NLR – neutrophil-to-lymphocyte ratio; PLR – platelet-to-lymphocyte ratio; PN – parenteral nutrition; SAH – subarachnoid hemorrhage; SD – standard deviation; SGA – subjective global assessment. |