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21 April 2022: Database Analysis

Effect of Alzheimer Disease on Prognosis of Intensive Care Unit (ICU) Patients: A Propensity Score Matching Analysis

Baohua Zhu 1ABC , Xiaoli Chen 2CD , Wei Li 3DF , Dandan Zhou 3AEF*

DOI: 10.12659/MSM.935397

Med Sci Monit 2022; 28:e935397

Table 6 Associations with 4-year mortality in critically ill patients who underwent surgery.

VariablesUnadjusted (n: 10916)P valueAdjusted (n: 10916)P value
HR (95%CI)HR (95%CI)
Age1.037 (1.034, 1.040)0.0001.027 (1.024, 1.030)0.000
Gender0.794 (0.734, 0.859)0.000
Weight0.988 (0.986, 0.990)0.0000.993 (0.991, 0.996)0.000
Congestive heart failure3.474 (3.116, 3.873)0.0002.302 (2.054, 2.581)0.000
Hypertension1.834 (1.616, 2.081)0.000
Chronic pulmonary1.543 (1.403, 1.697)0.0001.327 (1.205, 1.460)0.000
Diabetes0.967 (0.883, 1.059)0.472
Hypothyroidism1.108 (0.968, 1.269)0.135
Chronic kidney disease1.922 (1.709, 2.162)0.0001.218 (1.078, 1.377)0.002
SOFA1.095 (1.081, 1.109)0.0000.974 (0.956, 0.992)0.005
APS III1.022 (1.020, 1.024)0.0001.020 (1.018, 1.023)0.000
GCS0.960 (0.952, 0.968)0.0000.989 (0.979, 0.998)0.023
Alzheimer3.308 (2.439, 4.489)0.0001.839 (1.352, 2.501)0.000
SOFA – Sequential Organ Failure Assessment; APS III – Acute Physiology Score III; GCS – Glasgow Coma Score. HR – hazard ratio; CI – confidence interval.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750