Effect of Intracameral Carbachol and Epinephrine Use on Choroidal Thickness After Uncomplicated Phacoemulsification

Hasan Burhanettin Kaptı; Serkan Özen; Mustafa Gök

doi:10.12659/MSM.935315

02 May 2022: Clinical Research

Effect of Intracameral Carbachol and Epinephrine Use on Choroidal Thickness After Uncomplicated Phacoemulsification

Hasan Burhanettin Kaptı ^1ABEF* , Serkan Özen ^2CD , Mustafa Gök ^3EF

DOI: 10.12659/MSM.935315

Med Sci Monit 2022; 28:e935315

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Table 3 Comparison of preoperative and postoperative choroidal thickness measurements.

	Grup
	Control (n=34)	p*	Epinephrine (n=20)	p*	Carbachol (n=27)	p*

Before	192.65±59.42	0.953	198 [150–209]	0.179
1 day	193.24±47.51		193 [129–214]		171 [95–232]
1 week	191.24±45.1		205.5 [160–236]		170 [91–237]

Before	178.88±58.28	0.400	171 [111–202]	0.584
1 day	187.41±60.36		175 [145–204]
1 week	183.88±50.23		179 [131–202]		178 [91–254]

Before	174.35±58.36	0.691	142.5 [100–175]	0.009	186 [95–217]	0.773
1 day	184.41±59.79				204 [94–216]
1 week	179.59±48.28		153.5 [125–198]		205 [88–231]

Before	158.24±56.12	0.673	133.5 [95–151]	0.614	181 [92–205]	0.641
1 day	164.35±59.88		140 [111–144]		188 [91–211]
1 week	161.59±57.4		133 [121–159]		191 [81–200]

Before	134.06±60.91	0.149	110.5 [71–145]	0.058	166 [84–174]	0.247
1 day	142.12±54.46		115 [96–145]		156 [92–160]
1 week	140.76±54.37		122.5 [98–166]		157 [71–165]

Before	183.71±63.58	0.478	195 [129–220]	0.368	199 [115–259]	0.045
1 day	192.18±49.03		192 [146–224]		194 [114–245]
1 week	185.94±49.92		195 [148–227]		190 [108–220]

Before	183±69,92	0.164	190 [132–237]	0.273	194 [115–255]	0.717
1 day	194.71±60.64		177 [163–218]		198 [117–223]
1 week	179.71±64.51		173 [160–235]		201 [121–215]

Before	179.76±67.71	0.402	185 [122–225]	0.150	191 [133–207]	0.641
1 day	188.12±54.1		188.5 [156–202]		190 [130–232]
1 week	174.29±57		189 [155–235]		196 [132–263]

Before	171.35±56.99	0.252	176 [141–204]	0.794	188 [103–212]	0.368
1 day	187.82±55.23		202.5 [143–217]		185 [106–216]
1 week	171±48.15		183.5 [171–231]		184 [105–209]

Before	189.24±59.02	0.760	162.5 [134–210]	0.061	189 [100–256]	0.196
1 day	193.65±54.35		170 [144–221]		184 [92–253]
1 week	193.47±57.1		199.5 [145–228]		188 [89–261]

Before	178.65±60.11	0.030	159.5 [126–176]	0.407	188 [112–276]	0.972
1 day	184±50.16		162.5 [135–199]		183 [100–246]
1 week	180.12±52.57		171.5 [146–236]		185 [99–282]

Before	174.35±64.8	0,356	153.5 [124–185]	0.614	182 [104–266]	0.459
1 day	177.71±54.19		148.5 [126–181]		191 [100–284]
1 week	174.76±50.73		149 [124–221]		190 [92–280]

Before	167.12±48.43	0.141	146.5 [130–181]	0.202	180 [116–244]	0.717
1 day	174.06±48.87		146 [102–198]		179 [124–231]
1 week	173.71±42.61		181 [112–215]		176 [108–233]

Before	198.41±49.92	0.930	182 [151–212]	0.092	190 [136–256]	0.337
1 day	200.71±61.28		169.5 [160–246]		183 [142–265]
1 week	199.29±50.44		221 [163–257]		188 [145–264]

Before	192.94±53.03	0.053	174 [128–190]	0.301	188 [140–259]	0.895
1 day	204.24±56.84		165.5 [114–214]		189 [124–276]
1 week	201.88±57.3		171.5 [127–248]		191 [131–273]

Before	189.94±65.41	0.019	170 [122–206]	0.527	185 [195–245]	0.074
1 day	221.71±70.65		156 [128–204]		181 [160–248]
1 week	216±66.36		169 [135–210]		184 [152–231]

Before	185.88±70.06	0.911	157.5 [112–199]	0.301	180 [151–249]	0.328
1 day	199.53±61.33		155 [98–184]		174 [145–259]
1 week	198.94±57.9		195 [119–209]		156 [132–260]
^* Bonferroni correction was applied. Statistical significance level was accepted as p=(0.05/3)=0.0167. P values indicated in bold are statistically significant. Descriptive statistics presented given as mean±standard deviation and median (interquartile range) based on normality distribution. For comparisons given as mean±standard deviation, repeated measures one-way analysis of variance was used, while the Friedman test was used for comparisons given as median (interquartile range). SFCT – subfoveal choroidal thickness, N0.5 – choroidal thickness 0.5 mm nasal to the fovea; N1 – choroidal thickness 1 mm nasal to the fovea; N1.5 – choroidal thickness 1.5 mm nasal to the fovea; N2 – choroidal thickness 2 mm nasal to the fovea; T0.5 – choroidal thickness 0.5 mm temporal to the fovea; T1 – choroidal thickness 1mm temporal to the fovea; T1.5 – choroidal thickness 1.5 mm temporal to the fovea; T2 – choroidal thickness 2 mm temporal to the fovea; I0.5 – choroidal thickness 0.5 mm inferior to the fovea; I1 – choroidal thickness 1 mm inferior to the fovea; I1.5 – choroidal thickness 1.5 mm inferior to the fovea; I2 – choroidal thickness 2 mm inferior to the fovea; S0.5 – choroidal thickness 0.5 mm superior to the fovea; S1 – choroidal thickness 1 mm superior to the fovea; S1.5 – choroidal thickness 1.5 mm superior to the fovea; S2 – choroidal thickness 2 mm superior to the fovea.

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Effect of Intracameral Carbachol and Epinephrine Use on Choroidal Thickness After Uncomplicated Phacoemulsification

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