Retrospective Study from a Single Center to Evaluate the Association Between Sex and Serum Uric Acid Levels in 950 Patients with Atrial Fibrillation

12 May 2022: Clinical Research

Xia Zhong ^1ABCE , Huachen Jiao ^2BDFG* , Dongsheng Zhao ^1BCD , Jing Teng ^1ADF

DOI: 10.12659/MSM.935273

Med Sci Monit 2022; 28:e935273

Table 1 Baseline and clinical characteristics of control group and atrial fibrillation group.

Variable	Control group (n=963)	AF group (n=950)	P value
Age, years	67.92±11.66	68.61±10.34	0.171
Male, n (%)	470 (48.8)	479 (50.4)	0.480
Hypertension, n (%)	324 (33.6)	638 (67.2)	^*
CHD, n (%)	241 (25.0)	840 (88.4)	^*
Diabetes, n (%)	158 (16.4)	280 (29.5)	^*
Serum creatinine, μmoI/L	64.77±26.54	78.46±51.47	^*
AST, U/L	20.76±10.81	25.30±45.62	0.003^*
ALT, U/L	20.27±13.64	22.30±27.37	0.041^*
APOA1, g/L	1.23±0.25	1.13±0.26	^*
APOB, g/L	0.99±0.24	0.80±0.38	^*
ALB, g/L	40.11±4.12	38.05±4.64	^*
PAB, mg/L	222.57±55.02	195.61±59.43	^*
Lp (a), mg/dL	22.56±24.34	23.55±26.88	0.399
TG, mmol/L	1.38±1.24	1.24±0.88	0.004^*
TC, mmol/L	5.02±1.10	4.19±1.10	^*
LDL-C, mmol/L	2.96±0.86	2.50±0.90	^*
HDL-C, mmol/L	1.21±0.25	1.07±0.30	^*
SUA, mg/dL	5.21±1.50	5.71±1.91	^*
Male, mg/dL	5.80±1.46	6.07±1.89	^*
Female, mg/dL	4.64±1.30	5.34±1.86	^*
Hyperuricemia, n (%)	180 (18.69)	301 (31.68)	^*
Male	96 (9.97)	141 (14.84)	^*
Female	84 (8.72)	160 (16.84)	^*
Data are presented as mean±SD or n(%). AF – atrial fibrillation; CHD – coronary heart disease; AST – aspartate aminotransferase; ALT – alanine aminotransferase; APOA1 – serum apolipoprotein A1; APOB – serum apolipoprotein B; ALB – albumin; PAB – prealbumin; Lp (a) – lipoprotein (a); TG – triglyceride; TC – total cholesterol; LDL-C – low-density lipoprotein cholesterol; HDL-C – high-density lipoprotein cholesterol; SUA – serum uric acid. ^* Statistically significant value (