06 January 2022: Lab/In Vitro Research
Effect of Antibiotic Exposure on Upper Respiratory Tract Bacterial Flora
Hakan Korkmaz 1ABE* , Yeliz Çetinkol 2BD , Mukadder Korkmaz 3ACEF , Mustafa Kerem Çalgın 2BD , Yeliz Kaşko Arıcı 4CDDOI: 10.12659/MSM.934931
Med Sci Monit 2022; 28:e934931
Table 2 Comparison of the nasal and nasopharyngeal culture results of the antibiotic naïve group with antibiotic consumed patients with respect to antibiotic prescription periods.
| Antibiotic naïve | Antibiotic exposed: 0–1 month | Antibiotic exposed: 2–3 months | Antibiotic exposed: 4–6 months | Antibiotic exposed: 0–6 months | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n | % | n | % | p | n | % | p | n | % | p | n | % | p | ||
| Nose | Normal flora | 50 | 44.3 | 12 | 42.9 | 0.169 | 20 | 42.6 | 0.396 | 16 | 33.3 | 0.436 | 36 | 37.1 | 0.432 |
| Gram+ | 59 | 52.2 | 15 | 53.6 | 27 | 57.4 | 30 | 62.5 | 58 | 59.8 | |||||
| Gram− | 4 | 3.5 | 0 | 0 | 0 | 0.0 | 2 | 4.2 | 2 | 2.1 | |||||
| Fungus | 0 | 0.0 | 1 | 3.6 | 0 | 0.0 | 0 | 0.0 | 1 | 1.0 | |||||
| Nasopharynx | Normal flora | 56 | 49.6 | 11 | 39.3 | 0.271 | 16 | 34 | 0.093 | 27 | 56.3 | 0.458 | 43 | 44.3 | 0.135 |
| Gram+ | 44 | 38.9 | 16 | 57.1 | 26 | 55.3 | 17 | 35.4 | 46 | 47.4 | |||||
| Gram− | 8 | 7.1 | 1 | 3.6 | 5 | 10.6 | 4 | 8.3 | 8 | 8.2 | |||||
| Gram+ & Gram− | 5 | 4.4 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 | |||||
| n – number. Each value represents the statistical comparison of antibiotic naïve group with corresponding antibiotic exposure group. | |||||||||||||||