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02 January 2022: Clinical Research

Retrospective Study of 573 Patients with Heart Failure Evaluated for Coronary Artery Disease at Toulouse University Center, France

Antoine Deney 1ABCDEF* , Vanessa Nader 12ABCDEF* , Anthony Matta 13ABCDE , Romain Itier 1CDE , Pauline Fournier 1ABCD , Olivier Lairez 1ADF , Nathalie Pizzinat 4ACD , Didier Carrié 1ACD , Frédéric Boal 4ACD , Michel Galinier 1ACD , Oksana Kunduzova 4ACD , Rania Azar 2ACD , Jerome Roncalli 14ABCDEFG*

DOI: 10.12659/MSM.934804

Med Sci Monit 2022; 28:e934804

Table 5 Characteristics of the study population stratified by the presence of coronary artery disease.

Studied populationN=573No-CADN=253Significant CADN=320P-value
Age68.28±12.2564.90±13.53270.95±10.404
Male sex438 (76.44%)169 (66.80%)269 (84.06%)0.171
BMI27.89±18.10429.92±26.58126.28±4.8640.033
Atrial fibrillation174 (30.37%)79 (31.23%)95 (29.69%)0.691
HFrEF484 (84.47%)214 (84.58%)270 (84.37%)0.945
Chronic kidney disease266 (46.42%)84 (33.20%)182 (56.87%)
Dyslipidemia164 (28.62%)58 (22.92%)106 (33.13%)0.041
Diabetes171 (29.84%)58 (22.92%)113 (35.31%)0.010
Hypertension309 (53.93%)111 (43.87%)198 (61.87%)0.001
Smoking144 (25.13%)59 (23.32%)85 (26.56%)0.802
Family history89 (15.53%)42 (16.60%)47 (14.69%)0.261
Valvulopathy224 (39.09%)93 (36.76%)131 (40.93%)0.284
RVD110 (19.20%)52 (20.55%)58 (18.13%)0.535
TAPSE16.77±4.4516.05±4.3517.29±4.480.026
PAPSE41.38±13.3016.05±4.34717.29±4.4720.026
Pacemaker41 (7.16%)15 (5.93%)26 (8.13%)0.307
Defibrillator38 (6.63%)12 (4.74%)26 (8.13%)0.106
NYHA class
 123 (4.01%)10 (3.95%)14 (4.38%)0.964
 2143 (24.96%)60 (23.72%)83 (25.94%)
 3149 (26%)62 (24.51%)87 (27.19%)
 447 (8.20%)22 (8.70%)25 (7.81%)
Systolic blood pressure128.86±22.80127.64±22.37129.77±23.120.325
Diastolic blood pressure75.27±15.8476.30±17.9074.50±14.090.233
Heart rate82.07±20.7985.79±20.2679.25±20.780.001
Troponin143.87±543.08100.90±280.221169.84±652.320.368
NT-ProBNP5535.15±8523.845232.62±8247.125789.47±8758.010.485
β-blockers324 (56.54%)130 (51.38%)194 (60.63%)0.027
Diuretics328 (57.24%)137 (54.15%)191 (59.69%)0.169
Mineralocorticoids95 (16.58%)40 (15.81%)84 (17.19%)0.663
ACE/ARA289 (50.44%)114 (45.06%)175 (54.69%)0.025
ARNI45 (7.85%)21 (8.30%)24 (7.50%)0.724
Ivabradine7 (1.22%)2 (0.79%)5 (1.56%)0.472
SAPT172 (30.02%)44 (17.39%)128 (40.00%)
DAPT47 (8.20%)4 (1.58%)43 (13.44%)
DOAC+AVK164 (28.62%)70 (27.67%)94 (29.37%)0.637
AAP+OAC35 (6.11%)5 (1.977%)30 (9.38%)0.05
β-blockers480 (83.77%)213 (84.19%)267 (83.44%)0.851
Diuretics439 (76.61%)194 (76.68%)245 (76.56%)0.810
Mineralocorticoids231 (40.31%)114 (45.06%)117 (36.56%)0.048
ACE/ARA332 (57.94%)150 (59.29%)182 (56.88%)0.643
ARNI137 (23.90%)71 (28.06%)66 (20.62%)0.041
Ivabradine19 (3.32%)8 (3.16%)11 (3.44%)0.833
SAPT120 (20.94%)41 (16.20%)79 (24.68%)0.011
DAPT215 (37.52%)14 (5.53%)201 (62.81%)
DOAC+AVK217 (37.87%)106 (41.89%)111 (34.69%)0.480
AAP+OAC82 (14.31%)5 (1.98%)77 (24.06%)

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750