20 February 2022: Database Analysis
The Obesity-Related Metabolic Gene HSD17B8 Protects Against Breast Cancer: High RNA/Protein Expression Means a Better Prognosis
Yunmeng Nie ABEF , Fang Huang B , Lihua Lou B , Junbin Yan ABCDEF*DOI: 10.12659/MSM.934424
Med Sci Monit 2022; 28:e934424
Table 2 Differential expression of metabolic genes in overweight females.
| Symbol | Description | logFC | P value | Change |
|---|---|---|---|---|
| AKR1B10 | Aldo-keto reductase family 1 member B10 | 1.12065346 | 0.000140961 | Up |
| NCEH1 | Neutral cholesterol ester hydrolase 1 | 1.164559432 | 0.000309202 | Up |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | 0.718403707 | 0.000360012 | Up |
| LIPG | Lipase G, endothelial type | 0.558457824 | 0.001108886 | Up |
| ELOVL7 | ELOVL fatty acid elongase 7 | 0.640468036 | 0.00251885 | Up |
| GK | Glycerol kinase | 0.715113436 | 0.004721303 | Up |
| PFKFB4 | Fructose-2,6-biphosphatase 4 | 0.564762169 | 0.017233125 | Up |
| DGKI | Diacylglycerol kinase iota | 0.514214866 | 0.021602233 | Up |
| MYLIP | Myosin regulatory light chain interacting protein | 0.648838071 | 0.028529275 | Up |
| PMM1 | Phosphomannomutase 1 | −0.928028738 | 2.15E-06 | Down |
| GPAT3 | Glycerol-3-phosphate acyltransferase 3 | −2.032708972 | 2.32E-06 | Down |
| LPIN1 | Lipin 1 | −0.915227095 | 6.29E-06 | Down |
| HADH | Hydroxyacyl-CoA dehydrogenase | −0.824220026 | 7.15E-06 | Down |
| HSD17B8 | Hydroxysteroid 17-beta dehydrogenase 8 | −0.558910078 | 1.68E-05 | Down |
| TECR | Trans-2,3-enoyl-CoA reductase | −0.612995545 | 4.77E-05 | Down |
| APOB | Apolipoprotein B | −1.656658531 | 8.31E-05 | Down |
| FASN | Fatty acid synthase | −1.381302903 | 8.53E-05 | Down |
| GLYCTK | Glycerate kinase | −1.056885781 | 0.000167152 | Down |
| APOE | Apolipoprotein E | −1.356452072 | 0.000230256 | Down |
| PFKFB1 | Fructose-2,6-biphosphatase 1 | −0.881339318 | 0.000271712 | Down |
| CETP | Cholesteryl ester transfer protein | −1.620684825 | 0.000516983 | Down |
| ABCA1 | ATP binding cassette subfamily A member 1 | −0.606674508 | 0.000803253 | Down |
| DGAT1 | Diacylglycerol O-acyltransferase 1 | −0.7155092 | 0.000826011 | Down |
| ACACA | Acetyl-CoA carboxylase alpha | −0.585703299 | 0.001444855 | Down |
| PNPLA2 | Patatin like phospholipase domain containing 2 | −0.652268006 | 0.001543928 | Down |
| MOGAT1 | Monoacylglycerol O-acyltransferase 1 | −1.00537259 | 0.00161725 | Down |
| ACADL | Acyl-CoA dehydrogenase long chain | −0.654461844 | 0.001623612 | Down |
| SLC25A1 | Solute carrier family 25 member 1 | −0.64655005 | 0.001744174 | Down |
| AGPAT2 | 1-acylglycerol-3-phosphate O-acyltransferase 2 | −0.513983662 | 0.002620186 | Down |
| ELOVL5 | ELOVL fatty acid elongase 5 | −0.581297983 | 0.005167587 | Down |
| ELOVL3 | ELOVL fatty acid elongase 3 | −0.800030769 | 0.012447301 | Down |
| PLPP4 | Phospholipid phosphatase 4 | −0.639638082 | 0.028326607 | Down |
| PNPLA3 | Patatin like phospholipase domain containing 3 | −0.628606799 | 0.041133434 | Down |