15 January 2022>: Database Analysis
Prediction of Patient Survival with Psoas Muscle Density Following Transjugular Intrahepatic Portosystemic Shunts: A Retrospective Cohort Study
Biyu Zhang ABCDEF , Weimin Cai ABCDEF , Feng Gao BE , Xinran Lin BC , Ting Qian F , Kaier Gu B , Bingxin Song B , Tanzhou Chen A*DOI: 10.12659/MSM.934057
Med Sci Monit 2022; 28:e934057
Table 3 Characteristics of the study population, stratified by PMD measurement.a
Variables | All patients n=273 | Low PMD n=102 | High PMD n=171 | P valueb |
---|---|---|---|---|
Basic information | ||||
Survival | 242 | 79 | 163 | |
Age, y | 53.54±10.51 | 58.68±8.10 | 50.47±10.61 | |
Sex | ||||
Male | 194 | 61 | 133 | 0.002 |
Female | 79 | 41 | 38 | |
BMI | 22.87±3.15 | 24.08±3.49 | 22.29±2.83 | 0.016 |
Hypertension | 27 | 17 | 10 | 0.004 |
Smoking | 105 | 33 | 72 | 0.109 |
Splenectomy | 22 | 9 | 13 | 0.720 |
Etiology of cirrhosis | 0.217 | |||
Alcoholic | 53 | 23 | 30 | |
Viral (HBV or HCV) | 151 | 50 | 101 | |
Both alcohol and viral | 35 | 12 | 23 | |
Othersc | 34 | 17 | 17 | |
Reasons for TIPS | 0.099 | |||
EGVB | 246 | 87 | 159 | |
RF | 13 | 8 | 5 | |
Othersd | 14 | 7 | 7 | |
TIPS targeted puncture | 0.007 | |||
Left branch of the intrahepatic portal vein | 199 | 66 | 133 | |
Right branch of the intrahepatic portal vein | 61 | 30 | 31 | |
Otherse | 13 | 6 | 7 | |
Stent-graft diameters, mm | 8 (8–9) | 8 (8–10) | 8 (8–9) | 0.002 |
RBC, ×10 | 3.02±0.71 | 2.86±0.68 | 3.11±0.72 | 0.006 |
WBC, ×10 | 5.06±3.59 | 5.22±4.00 | 4.96±3.33 | 0.566 |
Lymphocyte, ×10 | 0.99±0.87 | 0.95±0.61 | 1.01±1.01 | 0.580 |
Neutrophil, ×10 | 3.34±2.68 | 3.50±2.97 | 3.24±2.49 | 0.447 |
Platelet, ×10 | 81.42±61.95 | 86.23±63.57 | 78.56±60.97 | 0.324 |
Hemoglobin, g/L | 85.78±24.74 | 83.50±21.44 | 87.13±26.49 | 0.241 |
Albumin, g/L | 30.18±5.39 | 28.97±5.98 | 30.89±4.88 | 0.004 |
Total bilirubin, μmol/L | 24.30±17.60 | 25.93±17.90 | 23.33±17.40 | 0.239 |
ALT, U/L | 43.02±106.98 | 40.66±75.20 | 44.43±122.25 | 0.778 |
AST, U/L | 55.24±100.32 | 56.39±63.21 | 54.55±117.16 | 0.884 |
Serum creatinine, μmol/L | 66.15±17.06 | 66.22±30.95 | 66.11±17.60 | 0.970 |
Serum sodium, mmol/L | 137.44±4.37 | 137.22±4.66 | 137.56±4.21 | 0.526 |
Prothrombin time, s | 17.34±2.67 | 17.72±3.52 | 17.11±1.98 | 0.067 |
INR | 1.42±0.24 | 1.42±0.25 | 1.42±0.23 | 0.986 |
Child-Pugh score | 7 (6–9) | 7 (6–9) | 9 (8–10) | |
MELD score | 11.45 (9.76–13.46) | 11.69 (9.59–14.02) | 11.18 (9.82–13.20) | 0.224 |
MELD-Na score | 10.91 (7.47–14.50) | 12.22 (7.31–15.27) | 10.62 (7.44–14.07) | 0.207 |
ALT – alanine aminotransferase; AST – aspartate aminotransferase; BMI – body mass index; EGVB – esophageal gastric-fundus variceal bleeding; HBV – hepatitis B virus; HCV – hepatitis C virus; HU – Hounsfield units; INR – international standardization ratio; MELD – model for end-stage liver disease; MELD-Na – composite index of model for end-stage liver disease and serum sodium; PMD – psoas muscle density; RBC – red blood cell count; RF – refractory ascites; TIPS – transjugular intrahepatic portosystemic shunt; WBC – white blood cell count. a Descriptive statistics are expressed as numbers or mean values (±SD), as appropriate. Continuous variables are expressed as means±SD or medians with interquartile ranges. b The test or the Mann-Whitney U test was used to compare 2 groups, and χ test or Fisher exact test was used to compare categorical variables. c Others included primary biliary cirrhosis, autoimmune diseases, Budd-Chiari syndrome, and cryptogenic cirrhosis. d Others included preventive therapy, portal system thrombosis, and alleviation of abdominal discomfort. e Others included portal vein trunk, right branches of the portal vein, and confluence of the left branches of the portal vein. |