04 February 2022: Clinical Research
Blood Pressure Rhythm and Blood Pressure Variability as Risk Factors for White Matter Lesions: A Cross-Sectional Study
Dong Zhang 1ABCDEF* , Mingli He 2ABCDG* , Qing He 1DEG* , Zeheng Li 3DEFDOI: 10.12659/MSM.933880
Med Sci Monit 2022; 28:e933880
Table 3 Logistic regression analysis of Fazekas grades and various factors.
| Variables | Univariate | Multivariate | ||
|---|---|---|---|---|
| OR (95% CI) | P value | OR(95% CI) | P value | |
| Age | 1.103 (1.050–1.160) | 1.083 (1.027–1.142) | 0.003 | |
| SBPCV | 1.556 (1.282–1.888) | 1.589 (1.273–1.983) | ||
| DBPCV | 1.374 (1.183–1.596) | 1.363 (1.150–1.616) | ||
| SBPDNR | 0.823 (0.754–0.899) | 0.815 (0.729–0.910) | ||
| DBPDNR | 0.906 (0.853–0.963) | 0.001 | 0.895 (0.831–0.964) | 0.003 |
| MSCBF(F3) | 1.000 | – | 1.000 | – |
| F2 | 1.334 (1.154–1.542) | 1.378 (1.141–1.665) | 0.001 | |
| F1 | 1.648 (1.388–1.957) | 1.739 (1.399–2.162) | ||
| F0 | 1.795 (1.500–2.148) | 1.847 (1.476–2.310) | ||
| MPCBF(F3) | 1.000 | – | 1.000 | – |
| F2 | 1.308 (1.127–1.518) | 1.272 (1.078–1.502) | 0.004 | |
| F1 | 1.748 (1.439–2.124) | 1.824 (1.446–2.301) | ||
| F0 | 1.926 (1.574–2.357) | 1.991 (1.565–2.532) | ||
| SBPCV – systolic blood pressure coefficient of variation; DBPCV – diastolic blood pressure coefficient of variation; DBPDNR – diastolic blood pressure day/night ratio; MSCBF – bilateral mean subcortical local cerebral blood flow; MPCBF – bilateral mean paraventricular cerebral blood flow; F – Fazekas grade. | ||||