16 August 2021: Clinical Research
Association Between Serum Albumin Levels and Obesity and Risk of Developing Chronic Kidney Disease Using Data from the Korean Multi-Rural Communities Cohort (MRCohort) Population Database
Kwang Ho Mun ABCDEFG*DOI: 10.12659/MSM.933840
Med Sci Monit 2021; 27:e933840
Table 2 Baseline characteristics of the participants by albumin and obesity.
| G1High albumin, low BMI | G2High albumin, high BMI | G3Low albumin, low BMI | G4Low albumin, high BMI | p | |
|---|---|---|---|---|---|
| n | 265 | 362 | 795 | 878 | |
| CKD onset, n (%) | 10 (3.8%) | 17 (4.7%) | 50 (6.3%) | 79 (9.0%) | |
| eGFR decline, n (%) | 29 (10.9%) | 33 (9.1%) | 99 (12.5%) | 108 (12.3%) | NS |
| Age, y | 58.7±9.5 | 57.0±8.4 | 61.4±9.9 | 58.6±9.3 | |
| Men, n (%) | 112 (42.3%) | 130 (35.9%) | 357 (44.9%) | 296 (33.7%) | |
| F/U time, months | 48.5±18.6 | 49.2±18.7 | 45.6±18.5 | 47.5±19.5 | |
| Smoke, n (%) | 45 (17.0%) | 36 (9.9%) | 146 (18.4%) | 102 (11.6%) | |
| Drink, n (%) | 109 (41.1%) | 168 (46.4%) | 356 (44.8%) | 402 (45.8%) | NS |
| Exercise, n (%) | 81 (30.6%) | 107 (29.6%) | 192 (24.2%) | 292 (33.3%) | |
| SBP, mmHg | 119.0±16.3 | 119.8±15.9 | 114.9±14.8 | 117.9±14.4 | |
| DBP, mmHg | 76.6±9.2 | 78.0±9.0 | 73.9±8.8 | 76.2±8.8 | |
| Glucose, mg/dL | 96.6±41.6 | 95.4±13.6 | 91.0±11.6 | 92.0±9.9 | |
| BMI, kg/m | 21.0±1.4 | 25.7±2.15 | 21.0±1.54 | 25.5±2.1 | |
| Total cholesterol, mg/dL | 204.0±34.0 | 213.1±35.7 | 187.6±32.4 | 195.3±32.6 | |
| Triglyceride, mg/dL | 102.3±40.8 | 105.6±38.7 | 93.7±33.6 | 101.7±37.8 | |
| HDL, mg/dL | 51.8±10.4 | 50.3±9.9 | 50.5±10.6 | 48.7±10.4 | |
| WBC, (10/L) | 6.4±1.9 | 6.7±2.0 | 6.3±1.9 | 6.3±1.7 | |
| CRP, mg/L | 1.3±4.6 | 1.6±3.1 | 1.8±5.5 | 1.5±2.8 | NS |
| AST, U/dL | 26.4±8.7 | 26.2±9.8 | 26.4±10.6 | 25.3±8.8 | NS |
| ALT, U/dL | 21.3±11.0 | 25.3±14.3 | 20.7±10.1 | 22.5±12.1 | |
| γ-GTP, U/dL | 26.5±58.6 | 29.4±36.5 | 24.5±42.6 | 23.9±30.0 | NS |
| Calorie, kcal/day | 1570.3±459.2 | 1593.5±471.6 | 1679.8±456.9 | 1631.5±484.5 | |
| Protein, g/day | 46.6±17.6 | 47.9±18.4 | 51.6±19.5 | 49.4±19.2 | |
| Albumin, mg/L | 4.7±0.1 | 4.7±0.1 | 4.3±0.2 | 4.3±0.2 | |
| eGFR, mL/min/1.73 m | 79.1±9.1 | 78.4±9.7 | 78.9±9.5 | 77.9±9.5 | NS |
| ALT – alanine transferase; AST – aspartate transaminase; BMI – body mass index; CKD – chronic kidney disease; CRP – c-reactive protein; DBP – diastolic blood pressure; eGFR – estimated glomerular filtration rate; F/U – follow-up; HDL – high-density lipoprotein; NS – not significant; γ-GTP – gamma-glutamyltransferase; SBP – systolic blood pressure; WBC – white blood cell. Data were expressed as mean±standard deviation for continuous variables and n%) for categorical variables. | |||||