10 November 2021>: Clinical Research
Evaluation of Susceptibility Genes/Loci Associated with Male Androgenetic Alopecia (MAGA) for Female-Pattern Hair Loss in a Chinese Han Population and a Brief Literature Review
Bo Liang 123AG* , Yantao Ding 123B* , Yi Zhou 123D* , Chunjun Yang 4BF* , Zhixiang Cheng 5FG*DOI: 10.12659/MSM.933424
Med Sci Monit 2021; 27:e933424
Table 2 Candidate variant analyses of MAGA susceptibility locus studies for FPHL.
Gene/locus | Population | Case-control association study | Results | Ref | |
---|---|---|---|---|---|
Cases | Controls | ||||
AR/EDA2R | UK | 145 | 179 | Subgroup analysis of UK patients revealed significant associations for seven variants in patients with an early age of onset | Redler et al., Br J Dermatol. 2012 []20 |
Germany | 85 | 150 | |||
Han Chinese | 200 | 200 | Negative | Rui et al., Dermatology. 2016 []21 | |
1p36 | UK | 145 | 469 | Negative | Redler et al., J Dermatol Sci. 2013 []22 |
Germany | 260 | ||||
2q35 | UK | 145 | 179 | Negative | Nuwayhid et al., Arch Dermatol Res. 2014 []23 |
Germany | 440 | 500 | |||
2q37 | UK | 145 | 469 | Negative | Redler et al., J Dermatol Sci. 2013 []22 |
Germany | 260 | ||||
3q25.1 | UK | 145 | 179 | Negative | Nuwayhid et al., Arch Dermatol Res. 2014 []23 |
Germany | 440 | 500 | |||
5q33.3 | UK | 145 | 469 | Negative | |
Germany | 260 | ||||
7p21.1 | UK | 145 | 469 | Negative | Redler et al., J Dermatol Sci. 2013 [22 |
Germany | 260 | ||||
7q11.22 | UK | 145 | 469 | Negative | |
Germany | 260 | ||||
12p12.1 | UK | 145 | 179 | Negative | Nuwayhid et al., Arch Dermatol Res. 2014 []23 |
Germany | 440 | 500 | |||
17q21.31 | UK | 145 | 469 | Negative | Redler et al., J Dermatol Sci. 2013 []22 |
Germany | 260 | ||||
18q21.1 | UK | 145 | 469 | Negative | |
Germany | 260 | ||||
20p11 | UK | 145 | 179 | Negative | Redler et al., Br J Dermatol. 2012 []20 |
Germany | 85 | 150 |