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28 October 2021: Clinical Research

Adverse Side Effects Associated with Corticosteroid Therapy: A Study in 39 Patients with Generalized Myasthenia Gravis

Stephen Johnson 1ABCDEF , Nakul Katyal 2DEF , Naureen Narula 3DEF , Raghav Govindarajan 2ABCDEF*

DOI: 10.12659/MSM.933296

Med Sci Monit 2021; 27:e933296

Table 2 Summary of patients’ clinical characteristics* (n=39).

CharacteristicNo. of patients (%)
Positive AChR antibody test result35 (89.7)
MGFA class
 2A14 (35.9)
 2B13 (33.3)
 3A8 (20.5)
 3B3 (7.7)
 4A1 (2.6)
Pre-existing comorbidities
 Anemia2 (5.1)
 Asthma8 (20.5)
 Atopic dermatitis1 (2.6)
 Benign prostatic hypertrophy1 (2.6)
 COPD16 (41.0)
 Coronary artery disease2 (5.1)
 Coronary heart disease1 (2.6)
 Depression4 (10.3)
 Diabetes5 (12.8)
 Gastroesophageal reflux disease8 (20.5)
 Hyperlipidemia4 (10.3)
 Hypertension22 (56.4)
 Hypothyroidism6 (15.4)
 Lung cancer1 (2.6)
 Pre-diabetes1 (2.6)
 Prostate cancer1 (2.6)
 Stroke4 (10.3)
 Vitamin D deficiency1 (2.6)
 None2 (5.1)
Number of comorbidities
 None2 (5.1)
 112 (30.8)
 29 (23.1)
 39 (23.1)
 ≥47 (17.9)
MG-ADL score
 23 (7.7)
 30
 40
 51 (2.6)
 64 (10.3)
 711 (28.2)
 815 (38.5)
 93 (7.7)
 101 (2.6)
 111 (2.6)
* Based on the last recorded value in the patient’s medical charts.
AChR – acetylcholine receptor; COPD – chronic obstructive pulmonary disease; MG-ADL – Myasthenia Gravis – Activities of Daily Living; MGFA – Myasthenia Gravis Foundation of America.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750