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18 October 2021: Lab/In Vitro Research

Salicylate Induced GABAR Internalization by Dopamine D1-Like Receptors Involving Protein Kinase C (PKC) in Spiral Ganglion Neurons

Jiangyuan Qin ABCDEF , Tingjia Wei BCD , Huiying Chen BCD , Xiaoyu Lin BC , Danxue Qin BC , Fangyu Wei BC , Peiqiang Liu BC , Wenhua Ye BC , Jiping Su ADG*

DOI: 10.12659/MSM.933278

Med Sci Monit 2021; 27:e933278

Supplementary Table 2 Data of Figure 3, GABARγ2 protein expression in the absence or presence of Bis I.

GroupsDensity (mean±SD)Relative expression as % of control (mean±SD)
Surface GABARγ2Surface Flotillin-1Total GABARγ2Total βIII-tubulinSurface GABARγ2Total GABARγ2
Bis I94.45±7.95157.94±22.5090.96±19.57192.76±9.1185.61±3.1798.08±17.81
SKF+Bis I75.75±6.36151.41±11.6691.72±21.93198.74±5.8570.81±6.8196.22±4.95
SKF+SCH+Bis I98.24±3.38146.92±8.5797.84±14.15201.31±19.5296.17±16.48101.81±7.07
SS+Bis I83.56±5.94199.48±24.6587.11±4.61186.47±1.8260.32±8.3090.77±13.90
SS+SKF+Bis I82.89±5.87198.91±23.9494.89±13.26182.13±24.4660.48±23.36101.21±27.66
SS+SKF+SCH+Bis I118.98±15.05196.13±17.81102.71±11.84178.71±16.7788.26±22.59111.68±22.99

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750