10 January 2022: Clinical Research
Expression of Long Non-Coding RNA (lncRNA) SNHG5 in Patients with Refractory Diabetic Macular Edema and Its Regulatory Mechanism
Junwen He 1ABEFG* , Zhang Rui 1BC , Jing Gao 2DE , Yanhong Chen 2DEF , Yanzi Li 1BCD , Tao Xu 1BDF , Shan Wang 2ABCE*DOI: 10.12659/MSM.932996
Med Sci Monit 2022; 28:e932996
Table 1 Demographic data of the studied groups.
| Variables | Idiopathic MH | DME | Refractory DME | P value* | P value** |
|---|---|---|---|---|---|
| Age (M±SD) | 56.13±12.62 | 56.50±12.95 | 53.98±13.90 | >0.05 | >0.05 |
| Course of disease | 4.18±3.03 | 6.94±4.89 | 9.25±5.41 | ||
| BMI (kg/m) (M±SD) | 21.57±1.04 | 24.60±3.09 | 26.89±2.45 | ||
| Female (%) | 43.33% | 36.54% | 42.11% | >0.05 | >0.05 |
| Male (%) | 56.67% | 63.46% | 57.89% | ||
| FBG (mmol/l) | 5.39±0.98 | 7.22±1.15 | 9.09±3.04 | ||
| HbA1C (%) | 4.95±0.46 | 7.74±2.03 | 9.51±1.48 | ||
| Proteinuria (g/Day) | 0.09±0.04 | 1.66±0.53 | 2.13±0.42 | ||
| Glycosuria (mg/dl) | 3.23±6.97 | 262.21±64.73 | 298.16±57.03 | ||
| Hemoglobin (g/L) | 124.77±18.59 | 130.10±18.58 | 126.02±18.45 | >0.05 | >0.05 |
| IOP (mmHg) | 15.03±2.11 | 14.85±2.09 | 15.42±1.84 | >0.05 | >0.05 |
| * Comparison between the DME group versus idiopathic macular hole (MH) group; ** comparison between the refractory DME group versus DME group. | |||||