27 June 2021>: Clinical Research
Analysis of Bone Strength and Bone Turnover Markers in Ankylosing Spondylitis with Radiological Hip Involvement
Wei Liu 1ABCDEFG , Hui Song 1ACDEFG* , Siliang Man 1BCD , Hongchao Li 1BDE , Liang Zhang 2BDDOI: 10.12659/MSM.932992
Med Sci Monit 2021; 27:e932992
Table 3 Bone turnover markers of AS with and without radiographic hip involvement.
RHI-AS(n=177) | WORHI-AS(n=162) | Unadjusted | Adjusted for age and BMI | |||
---|---|---|---|---|---|---|
P | OR (95% CI) | P | OR (95% CI) | |||
TP1NP (ng/ml), median (Q1, Q3) | 64.41 (48.0, 90.09) | 58.47 (40.2, 69.11) | 0.004 | 1.011 (1.004, 1.019) | 0.185 | 1.006 (0.997, 1.014) |
β-CTx (ng/ml), median (Q1, Q3) | 0.63 (0.44, 0.83) | 0.64 (0.51, 0.79) | 0.773 | 1.058 (0.723, 1.549) | 0.677 | 1.021 (0.927, 1.124) |
OC (ng/ml), median (Q1, Q3) | 24.07 (17.13, 31.44) | 20.43 (15.77, 25.5) | 0.001 | 1.041 (1.016, 1.067) | 0.135 | 1.020 (0.994, 1.047) |
25(OH)VD3 (ng/ml), median (Q1, Q3) | 15.11 (10.55, 24.16) | 16.08 (11.41, 24.52) | 0.307 | 0.988 (0.965, 1.011) | 0.229 | 0.985 (0.961, 1.010) |
PTH (pg/ml), median (Q1, Q3) | 33.65 (25.4, 47.23) | 37.0 (25.8, 50.9) | 0.255 | 0.992 (0.979, 1.006) | 0.683 | 1.003 (0.989, 1.018) |
RHI-AS – ankylosing spondylitis with radiographic hip involvement; WORHI-AS – ankylosing spondylitis without radiographic hip involvement; TP1NP – total procollagen I N-terminal propeptide; β-CTx – beta C-terminal cross-linked telopeptides of type I collagen; OC – osteocalcin; 25(OH)VD3 – 25-dihydroxyvitamin D3, PTH – parathyroid hormone. |