27 September 2021: Database Analysis
Postoperative Neutrophil-to-Lymphocyte Ratio Is Associated with Mortality in Adult Patients After Cardiopulmonary Bypass Surgery: A Cohort Study
Yanhong Zhu 1BCE , Wenyong Peng 2BDF , Shuai Zhen 2BEF , Xiaofeng Jiang 2AC*DOI: 10.12659/MSM.932954
Med Sci Monit 2021; 27:e932954
Table 1 Comparisons of demographics between survivors and non-survivors.
| Characteristics | Survivors (n=550) | Non-survivors (n=25) | p Value |
|---|---|---|---|
| Age (year) | 67.1±12.29 | 70.6±15.9 | 0.182 |
| Sex, n (%) | 0.317 | ||
| Male | 382 (69.5%) | 15 (60.0%) | |
| Female | 168 (30.5%) | 10 (40.0%) | |
| BMI (Kg/m) | 29.0±6.3 | 30.9±8.0 | 0.144 |
| Ethnicity, n (%) | 0.973 | ||
| White | 431 (78.4%) | 20 (80.0%) | |
| Black | 21 (3.8%) | 1 (4.0%) | |
| Other | 98 (17.8%) | 4 (16.0%) | |
| HR (beats/min) | 83.9±11.6 | 88.2±17.5 | 0.077 |
| RR (beats/min) | 14.5±4.2 | 16.5±5.2 | 0.020 |
| SBP, mmHg | 114.1±17.5 | 102.8±13.5 | 0.002 |
| DBP, mmHg | 60.2±11.5 | 54.1±14.4 | 0.010 |
| MBP, mmHg | 78.0±12.4 | 70.7±10.1 | 0.004 |
| SPO2, % | 98.8±2.4 | 97.3±3.8 | 0.005 |
| Hemoglobin, g/dL | 9.9±2.3 | 9.8±2.4 | 0.879 |
| Hematocrit,% | 28.5±6.7 | 29.6±6.8 | 0.933 |
| WBC count, 10/L | 12.9±5.0 | 13.4±4.9 | 0.659 |
| Neutrophil, (%) | 80.0±8.0 | 82.7±5.8 | 0.107 |
| Lymphocyte, (%) | 14.2±7.1 | 10.6±5.1 | 0.014 |
| NLR | 9.1±9.2 | 24.3±26.4 | |
| Platelet count, 10/L | 176.0±67.6 | 191.7±87.5 | 0.262 |
| Serum sodium, mmol/l | 136.3±3.1 | 136.3±3.5 | 0.986 |
| Serum potassium, mmol/l | 4.7±0.8 | 4.9±1.2 | 0.100 |
| Serum chloride, mmol/l | 105.7±4.4 | 106.2±6.1 | 0.593 |
| Anion gap, mmol/l | 11.5±2.9 | 14.3±3.5 | |
| Serum bicarbonate, mmol/l | 24.0±2.6 | 21.3±3.5 | |
| BUN, mg/dL | 20.2±11.5 | 32.1±17.7 | |
| SCr, mg/dL | 1.1±0.7 | 1.9±1.3 | |
| Serum glucose, mg/dl | 141.0±43.1 | 153.6±58.0 | 0.159 |
| Serum lactate, mmol/l | 2.4±1.3 | 3.3±2.1 | 0.001 |
| Vasoactive drug use, n (%) | 543 (98.7%) | 25 (100%) | 0.731 |
| Endocarditis | 17 (3.1%) | 3 (12.0%) | 0.051 |
| CHF | 171 (31.1%) | 13 (52.0%) | 0.028 |
| AF | 271 (49.3%) | 17 (68.0%) | 0.067 |
| Chronic renal disease | 14 (2.5%) | 3 (12.0%) | 0.033 |
| Chronic liver disease | 5 (0.9%) | 0 (0) | 0.800 |
| COPD | 5 (0.9%) | 1 (4.0%) | 0.235 |
| CAD | 396 (72.0%) | 16 (64.0%) | 0.385 |
| Stroke | 27 (4.9%) | 3 (12.0%) | 0.136 |
| Malignancy | 12 (2.2%) | 0 (0) | 0.584 |
| Pneumonia | 53 (9.6%) | 9 (36.0%) | 0.001 |
| APS III | 36 (28, 49) | 50 (40, 73) | |
| Data are presented as the mean±SD and n (%). BMI – body mass index; HR – heart rate; RR – respiratory rate; SBP – systolic blood pressure; DBP – diastolic blood pressure; MBP – mean blood pressure; SPO2 – percutaneous oxygen saturation; WBC – white blood cell; NLR – neutrophil-to-lymphocyte ratio; SCr – serum creatine; BUN – blood urea nitrogen; CHF – congestive heart failure; AF – atrial fibrillation; COPD – chronic obstructive pulmonary disease; CAD – coronary artery disease; APS III – acute physiology score III. | |||