Performance of Diagnostic Model for Differentiating Between COVID-19 and Influenza: A 2-Center Retrospective Study

12 May 2021: Clinical Research

Jingwen Li ^1E , Simin Li ^2B , Xiaoming Qiu ^3B , Wenyan Zhu ^2F , Linfeng Li ^2F , Bo Qin ^1A*

DOI: 10.12659/MSM.932361

Med Sci Monit 2021; 27:e932361

Table 2 Initial laboratory indices of patients with COVID-19 and influenza.

Variables	COVID-19 (n=282)	Influenza (n=211)	P value
White blood cell count, ×10/L	5.2±2.2	7.6±3.9	^*
Eosinophil cell count, ×10/L	0.1±0.3	0.1±0.8	0.031^*
Neutrophil count, ×10/L	3.5±2.1	5.6±3.7	^*
Lymphocyte count, ×10/L	1.3±2.6	1.3±0.8	0.066
Hemoglobin, g/L	133.9±24.3	131.8±22.0	0.410
Platelet count, ×10/L	187.1±67.7	195.7±85.8	0.098
Prothrombin time, s	11.8±2.6	12.5±2.4	0.020^*
Activated partial thromboplastin times, s	36.4±6.5	30.5±6.5	^*
D-dimer, mg/L	0.4±0.9	1.8±1.2	^*
Albumin, g/L	40.0±6.2	37.0±7.3	^*
Alanine aminotransferase, U/L	31.2±28.4	76.5±166.9	0.001^*
Aspartate aminotransferase, U/L	33.5±30.5	68.3±117.6	0.005^*
Bilirubin, μmol/L	11.2±8.5	26.4±63.7	^*
Potassium, mmol/L	4.2±0.5	4.0±0.6	^*
Sodium, mmol/L	139.9±3.7	138.9±4.4	0.003^*
Creatinine, μmol/L	70.1±31.7	87.5±80.7	0.005^*
C-reactive protein, mg/L	22.3±23.2	49.9±62.4	^*
Creatine kinase, U/L	129.6±183.4	220.3±369.0	0.176
Lactate dehydrogenase, U/L	257.2±111.8	376.2±391.3	0.097
^*