26 October 2021>: Clinical Research
Expression of Interleukin-17, Tumor Necrosis Factor-Alpha, and Matrix Metalloproteinase-8 in Patients with Chronic Peri-Implant Mucositis
Darius Gleiznys 1ABCDEFG* , Albertas Kriauciunas 1BCDE , Julius Maminskas 1AB , Arturas Stumbras 2FG , Dalia Giedrimiene 3CD , Christine Niekrash 4CDE , Alvydas Gleiznys 1AD , Jurgina Sakalauskiene 1ABEF , Astra Vitkauskiene 5ACDEDOI: 10.12659/MSM.932243
Med Sci Monit 2021; 27:e932243
Table 3 The levels of MMP-8, IL-17, and TNF-α in peri-implant crevicular fluid of healthy subjects and the mucositis patients untreated and treated groups.
Study groups | MMP-8 | IL-17 | TNF-α |
---|---|---|---|
Median [25–75%] | |||
HP, n=30 | 0.99 [0.68–1.4] | 1.87 [0.83–3.24] | 0.7 [0.53–0.74] |
MP, n=30 | 3.27 [2.46–7.24] | 17.94 [14.44–20.56] | 3.08 [2.69–3.82] |
TP, n=30 | 1.70 [0.53–3.05] | 6.35 [4.43–6.75] | 1.52 [1.17–1.88] |
χ=39.671, df=2, | χ=77.615, df=2, | χ=79.137, df=2, | |
χ – by Kruskal-Wallis test, multiple comparisons by Mann-Whitney test; df – degrees of freedom. HP – healthy subjects; MP – patients with untreated peri-implant mucositis; TP – patients treated with mechanical anti-infective therapies for mucositis. |