10 September 2021: Clinical Research
Epidemiology and Mortality of Sepsis in Intensive Care Units in Prefecture-Level Cities in Sichuan, China: A Prospective Multicenter Study
Lianghai Cao 1ABE* , Min Xiao 2ABE* , Yong Wan 3AE* , Chaogui Zhang 1B , Xiaofeng Gao 4C , Xuemei Chen 5B , Xiangde Zheng 6B , Xianhua Xiao 7B , Mingquan Yang 8B , Yuanhua Zhang 9BDOI: 10.12659/MSM.932227
Med Sci Monit 2021; 27:e932227
Table 4 Laboratory indices, severity scores, and hospitalization characteristics of sepsis patients during ICU admission.
| All patients (n=294) | Survival (n=125) | Death (n=169) | P | |
|---|---|---|---|---|
| HGB minimum, g/L, median (Q1, Q3) | 86 (70–107)b | 86 (73–106) | 87 (69–109)b | 0.875 |
| PLT minimum, ×10/L, median (Q1, Q3) | 160 (91–245)b | 164 (99–268) | 156 (84–228)b | 0.101 |
| PCT maximum, ng/ml, median (Q1, Q3) | 18.24 (4.69–58.11)d | 20.89 (6.47–56.42) | 16.81 (3.98–60.00)d | 0.381 |
| ALB minimum, g/L, median (Q1, Q3) | 26.0 (23.0–29.3)c | 26.8 (23.1–29.2)a | 25.8 (22.9–29.4)b | 0.748 |
| PALB minimum, mg/L, median (Q1, Q3) | 49.4 (26.6–79.0)o | 55.2 (31.7–88.2)k | 45.8 (25.3–73.5)n | 0.147 |
| Blood total Ca minimum, mmol/L, median (Q1, Q3) | 1.84 (1.61–2.00)l | 1.83 (1.67–1.97)g | 1.85 (1.52–2.01)i | 0.588 |
| Blood P minimum, mmol/L, median (Q1, Q3) | 0.78 (0.54–1.08)m | 0.69 (0.49–0.90)h | 0.90 (0.58–1.36)j | |
| LAC maximum, mmol/L, median (Q1, Q3) | 4.3 (2.6–7.5)c | 3.3 (2.1–4.7)b | 6.5 (3.2–10.1)a | |
| PT maximum, s, median (Q1, Q3) | 17.6 (15.5–21.2)g | 17.0 (14.7–19.7)f | 18.0 (15.3–22.9)e | 0.035 |
| APTT maximum, s, median (Q1, Q3) | 47.5 (39.3–61.9)f | 45.0 (38.8–54.4)c | 48.9 (39.6–67.9)c | 0.029 |
| FIB minimum, g/L, median (Q1, Q3) | 3.22 (1.81–4.64)c | 3.48 (2.15–4.77)a | 3.17 (1.60–4.56)b | 0.251 |
| INR maximum, median (Q1, Q3) | 1.49 (1.25–1.81)d | 1.44 (1.24–1.66)b | 1.52 (1.27–1.94)b | 0.063 |
| APACHEII on day 1, median (Q1, Q3) | 26 (21–32)a | 23 (17.5–26) | 29 (24–36)a | |
| SOFA score on day 1, median (Q1, Q3) | 10 (7–12)a | 8 (6–10) | 11 (8–14)a | |
| Duration of ventilation, hours, median (Q1, Q3) | 48 (11–130) | 37 (0–116) | 55 (17–140) | 0.049 |
| ICU stay, days, median (Q1, Q3) | 4 (2–8) | 5 (3–9) | 3 (1–7) | |
| Hospital stay, days, median (Q1, Q3) | 8 (2–19) | 18 (11–26.5) | 3 (1–8) | |
| IQR: P25-P75. ALB – albumin; APACHE II – Acute Physiology and Chronic Health Evaluation II; APTT – activated partial thrombin time; FIB – fibrinogen; HGB – hemoglobin; ICU – Intensive Care Unit; INR – International Standardized Ratio; LAC – lactic acid; PALB – prealbumin; PCT – procalcitonin; PLT – platelet; PT – prothrombin time; SOFA – Sequential Organ Failure Assessment. Number of Untested Cases: a =1, b =2, c =3, d =4, e =5, F =6, g =11, h =14, i =19, j =24, k =26, l =30, m =38, n =49, o =75. | ||||