07 August 2021: Clinical Research
A Retrospective Study of 268 Patients with SARS-CoV-2 Infection to Evaluate the Association Between Blood Glucose and Severity of COVID-19 Pneumonia and Patient Mortality
Yaoyao Sun 12CDE* , Nan Jiang 1ABD* , Zhijun Li 2CD , Xinwei Li 2DF , Bo Yang 3B , Daoyuan Si 4D , Piyong Ma 5BF , Jinnan Zhang 6BF , Ningning Jia 2EF , Mengdi Jin 2E , Yang He 2C , Xingyao Cui 2D , Tianji Liu 1AB* , Qiong Yu 2ABCDF*DOI: 10.12659/MSM.932156
Med Sci Monit 2021; 27:e932156
Table 3 Univariate and multivariate survival analysis of overall survival in patients with COVID-19.
| Characteristics | Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|---|
| Log-rank χ2 | P | HR | 95% CI | P | |
| Age, years | 0.938 | 0.333 | |||
| Ref | |||||
| ≥60 | 1.129 | 0.538–2.368 | 0.748 | ||
| Sex | 2.914 | 0.088 | |||
| Female | Ref | ||||
| Male | 0.735 | 0.406–1.330 | 0.309 | ||
| Blood glucose, mmol/L | 41.608 | ||||
| Q1 | Ref | ||||
| Q2 | 4.221 | 0.937–19.012 | 0.061 | ||
| Q3 | 10.128 | 2.368–43.306 | 0.002 | ||
| Leukocyte count, ×10/L | 38.606 | ||||
| Normal | Ref | ||||
| Unnormal | 1.283 | 0.624–2.638 | 0.498 | ||
| Neutrophil count, ×10/L | 52.032 | ||||
| Normal | Ref | ||||
| Unnormal | 3.456 | 1.553–7.689 | 0.002 | ||
| Lymphocyte count, ×10/L | 27.903 | ||||
| Normal | Ref | ||||
| Unnormal | 4.579 | 1.360–15.416 | 0.014 | ||
| ALT, U/L | 0.488 | 0.485 | |||
| Normal | Ref | ||||
| Unnormal | 0.870 | 0.464–1.632 | 0.665 | ||
| AST, U/L | 21.184 | ||||
| Normal | Ref | ||||
| Unnormal | 1.656 | 0.863–3.176 | 0.129 | ||
| LDH, U/L | 10.629 | 0.001 | |||
| Normal | Ref | ||||
| Unnormal | 2.031 | 0.256–16.088 | 0.502 | ||
| Total bilirubin, μmol/L | 14.550 | ||||
| Normal | Ref | ||||
| Unnormal | 2.687 | 1.075–6.716 | 0.035 | ||
| Creatinine, μmol/L | 6.585 | 0.010 | |||
| Normal | Ref | ||||
| Unnormal | 1.454 | 0.820–2.579 | 0.200 | ||
| Q1, | |||||