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12 August 2021: Clinical Research

Renal Cortical Perfusion Estimated in Color Doppler Dynamic Tissue Perfusion Measurement in Patients Treated with Levothyroxine Following Total Thyroidectomy for Resectable Thyroid Cancer Is Independently Associated with Free Thyroxine: A Single-Center Prospective Study

Arkadiusz Lubas 1ABCDEF* , Anna Grzywacz 1DEF , Stanisław Niemczyk 1BEG , Grzegorz Kamiński 2ABE , Marek Saracyn 2ABDEF

DOI: 10.12659/MSM.932096

Med Sci Monit 2021; 27:e932096

Table 1 Demographic data and results of performed tests in all investigated patients.

VariableMean±SDMedian (IQR)Reference range*
Sex (F/M)27/9n.a.
Age (y)38.2±11.636.0 (11.7)18.0–50.0
BMI (kg/m)24.4±3.723.6 (3.6)18.5–24.9
SBP (mmHg)125.6±18.1119.0 (25.5)
DBP (mmHg)78.4±10.977.5 (17.5)
MAP (mmHg)94.3±12.892.5 (18.0)70–110
TSH (μIU/mL)3.17±7.000.24 (1.61)0.27–4.20
FT (pmol/L)19.59±3.4019.9 (4.57)12.0–22.0
FT (pmol/L)4.84±0.834.79 (1.40)3.2–6.9
Levothyroxine dose (μg/24 hrs)139±34131 (25.0)n.a.
Creatinine (μmol/L)68.95±11.4966.32 (8.84)
eGFR (ml/min/1.73 m)103.9±13.7102.5 (18.5)>90
CRP (nmol/L)11.24±13.715.71 (9.52)
Kidney length (mm)112.0±10.0113.0 (14.5)90.0–130.0
Cortical thickness (mm)14.1±2.314.0 (2.0)>10
cRI (ratio)0.627±0.0690.628 (0.089)n.a.
RCP (cm/s)0.723±0.3210.626 (0.417)n.a.
BMI – body mass index, CRP – C-reactive protein; cRI - cortical resistive index; DBP – diastolic blood pressure; eGFR – estimated glomerular filtration rate based on the CKD-EPI (chronic kidney disease-epidemiology) creatinine equation (2009); FT – triiodothyronine free hormone; FT – thyroxine free hormone; IQR – interquartile range; MAP – mean arterial blood pressure; RCP – renal cortical perfusion; SBP – systolic blood pressure; TSH – thyroid-stimulating hormone; n.a. – not available;
* reference values used by local laboratory unit and departments.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750