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30 September 2021: Clinical Research

Prospective Study on the Postoperative Use of Levosimendan After Conventional Heart Valve Replacement

Wei Sheng ABCDEF* , Hui Qiao ABCDEF* , Zhaozhuo Niu BCE , Tianyi Wang BCE , Haoyou Li CDE , Wenfeng Zhang CDE , Jiantao Wu CDE , Xiao Lv ADEF*

DOI: 10.12659/MSM.932001

Med Sci Monit 2021; 27:e932001

Table 2 Comparison of cardiac function at different time points between the 2 groups.

ParametersTime (after surgery)Levosimendan (n=93)Control (n=92)χ2 or t valueP value
CO (L/min, mean±SD)1 day4.5±0.94.2±0.82.3950.018
3 days4.7±1.14.3±0.92.7050.008
7 days5.2±1.04.4±1.15.1770.000
LVEF (%, mean±SD)1 day51.3±2.248.3±2.19.4860.000
3 days53.5±2.448.9±2.113.8680.000
7 days55.7±2.550.5±2.215.0120.000
BNP (pg/mL, mean±SD)1 day520.7±47.2986.5±55.161.7720.000
3 days420.5±39.6747.3±50.249.1880.000
7 days312.5±34.6455.4±45.224.1610.000
CO – cardiac output; LVEF – left ventricular ejection fraction; BNP – B-type natriuretic peptide.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750