Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

30 September 2021: Clinical Research

Prospective Study on the Postoperative Use of Levosimendan After Conventional Heart Valve Replacement

Wei Sheng ABCDEF* , Hui Qiao ABCDEF* , Zhaozhuo Niu BCE , Tianyi Wang BCE , Haoyou Li CDE , Wenfeng Zhang CDE , Jiantao Wu CDE , Xiao Lv ADEF*

DOI: 10.12659/MSM.932001

Med Sci Monit 2021; 27:e932001

Table 1 Comparison of preoperative and intraoperative clinical characteristics between the 2 groups.

CharacteristicsLevosimendan (n=93)Control (n=92)χ2 or tP value
Age (year, mean±SD)66.5±7.465.9±7.20.5590.577
Sex (%)0.5230.470
 Male59 (63.4)63 (68.5)
 Female34 (36.6)29 (31.5)
Body mass index (Kg/m)22.8±3.123.5±3.21.5110.133
Hypertension (%)19 (20.4)17 (18.5)0.1120.737
Diabetes mellitus (%)8 (8.6)7 (7.6)0.0610.805
Chronic obstructive pulmonary disease (%)3 (3.2)2 (2.2)0.1950.659
Smoking history (%)51 (54.8)53 (57.6)0.1440.704
NYHA classification (%)0.2530.615
 Class II~III72 (77.4)74 (80.4)
 Class IV21 (22.6)18 (19.6)
Preoperative BNP (pg/mL, mean±SD)285.6±23.9279.8±22.31.7060.090
Preoperative serum creatinine (μmol/L, SD) (umol/L, mean±SD)85.2±11.386.5±11.90.7620.447
Preoperative LVEF (%, mean±SD)52.1±2.451.6±2.11.5070.133
Operation (%)0.504>0.05
 MVR47 (50.5)42 (45.7)
 AVR26 (28.0)27 (29.3)
 DVR20 (21.5)23 (25.0)
CPB time115.2±10.5117.4±11.51.3590.176
Cross-clamping time78.5±6.880.2±7.11.6630.098
NYHA – New York Heart Association; BNP – B-type natriuretic peptide; LVEF – left ventricular ejection fraction; MVR – mitral valve replacement; AVR – aortic valve replacement; DVR – double valve replacement; CPB – cardiopulmonary bypass.

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750