25 August 2021: Clinical Research
“Obesity Paradox” in Acute Respiratory Distress Syndrome Among Patients Undergoing Cardiac Surgery: A Retrospective Study
Yan Liu 1ABCDEFG , Man Song 1BCDF , Lixue Huang 2BCDF , Guangfa Zhu 13ACG*DOI: 10.12659/MSM.931808
Med Sci Monit 2021; 27:e931808
Supplementary Table 3 Baseline characteristics of patients with acute respiratory distress syndrome (n=202).
| BMI | <18.5 | ≥18.5, <25 | ≥25, <30 | ≥30 | P value |
|---|---|---|---|---|---|
| N (%) | 14 (6.93%) | 108 (53.47%) | 62 (30.69%) | 18 (8.91%) | |
| Age, years | 51.79±16.16 | 57.07±14.19 | 62.39±10.98 | 56.83±13.90 | 0.019 |
| Smoking index | 300.00 (200.00–550.00) | 500.00 (400.00–800.00) | 550.00 (300.00–800.00) | 800.00 (600.00–1050.00) | 0.354 |
| EF value before surgery, % | 39.21±31.03 | 52.04±23.49 | 48.34±26.01 | 52.06±25.20 | 0.296 |
| Hemoglobin level before surgery, g/l | 111.21±16.68 | 120.33±23.74 | 131.61±21.79 | 129.00±23.64 | 0.002 |
| Albumin level before surgery, g/l | 41.00±3.57 | 37.81±9.43 | 36.97±7.30 | 36.00±10.23 | 0.365 |
| APACHE II value | 17.79±4.98 | 19.43±5.28 | 20.52±6.23 | 20.00±7.10 | 0.378 |
| Duration of surgery, hours | 5.48±1.68 | 6.53±2.77 | 6.25±2.90 | 6.26±(2.89 | 0.586 |
| Blood loss, ml | 700.00 (400.00–800.00) | 1000.00 (700.00–1300.00) | 1000.00 (725.00–1500.00) | 750.00 (500.00–1425.00) | 0.285 |
| Transfusion of red blood cells, ml | 400.00 (300.00–575.00) | 800.00 (400.00–1000.00) | 800.00 (410.00–1181.50) | 700.00 (400.00–900.00) | 0.310 |
| Transfusion of plasma cells, ml | 400.00 (0.00–475.00) | 400.00 (0.00–400.00) | 200.00 (0.00–400.00) | 0.00 (0.00–150.00) | 0.186 |
| EF value after surgery, % | 30.50±23.98 | 49.31±17.24 | 50.32±16.42 | 54.78±22.05 | |
| Duration of incubation time, hours | 41.00 (0.00–144.00) | 115.50 (45.50–263.85) | 115.10 (48.67–394.73) | 360.00 (192.00–483.25) | 0.001 |
| Gender, % | 0.010 | ||||
| Male | 12 (85.71%) | 78 (72.22%) | 34 (54.84%) | 8 (44.44%) | |
| Female | 2 (14.29%) | 30 (27.78%) | 28 (45.16%) | 10 (55.56%) | |
| History of cardiac surgery, % | 0.003 | ||||
| No | 14 (100.00%) | 88 (81.48%) | 61 (98.39%) | 17 (94.44%) | |
| Yes | 0 (0.00%) | 20 (18.52%) | 1 (1.61%) | 1 (5.56%) | |
| History of hypertension, % | |||||
| No | 13 (92.86%) | 60 (55.56%) | 22 (35.48%) | 0 (0.00%) | |
| Yes | 1 (7.14%) | 48 (44.44%) | 40 (64.52%) | 18 (100.00%) | |
| History of diabetes, % | 0.315 | ||||
| No | 13 (92.86%) | 85 (78.70%) | 46 (74.19%) | 12 (66.67%) | |
| Yes | 1 (7.14%) | 23 (21.30%) | 16 (25.81%) | 6 (33.33%) | |
| History of AMI, % | 0.013 | ||||
| No | 12 (85.71%) | 87 (80.56%) | 38 (61.29%) | 16 (88.89%) | |
| Yes | 2 (14.29%) | 21 (19.44%) | 24 (38.71%) | 2 (11.11%) | |
| Emergency surgery, % | 0.090 | ||||
| No | 14 (100.00%) | 95 (87.96%) | 50 (80.65%) | 13 (72.22%) | |
| Yes | 0 (0.00%) | 13 (12.04%) | 12 (19.35%) | 5 (27.78%) | |
| Type of surgery, % | 0.019 | ||||
| Isolated valvular surgery or isolated CABG surgery | 8 (57.14%) | 50 (46.30%) | 37 (59.68%) | 9 (50.00%) | |
| Valvular combined with CABG surgery | 3 (21.43%) | 20 (18.52%) | 4 (6.45%) | 2 (11.11%) | |
| Aortic surgery | 0 (0.00%) | 15 (13.89%) | 16 (25.81%) | 6 (33.33%) | |
| Others | 3 (21.43%) | 23 (21.30%) | 5 (8.06%) | 1 (5.56%) | |
| Infection after surgery | 0.745 | ||||
| No | 9 (64.29%) | 67 (62.04%) | 36 (58.06%) | 13 (72.22%) | |
| Yes | 5 (35.71%) | 41 (37.96%) | 26 (41.94%) | 5 (27.78%) | |
| IABP after surgery | |||||
| No | 11 (78.57%) | 81 (75.00%) | 51 (82.26%) | 15 (83.33%) | 0.676 |
| Yes | 3 (21.43%) | 27 (25.00%) | 11 (17.74%) | 3 (16.67%) | |
| ECMO after surgery | 0.352 | ||||
| No | 12 (85.71%) | 95 (87.96%) | 54 (87.10%) | 13 (72.22%) | |
| Yes | 2 (14.29%) | 13 (12.04%) | 8 (12.90%) | 5 (27.78%) | |
| CRRT after surgery | 0.920 | ||||
| No | 9 (64.29%) | 71 (65.74%) | 43 (69.35%) | 13 (72.22%) | |
| Yes | 5 (35.71%) | 37 (34.26%) | 19 (30.65%) | 5 (27.78%) | |
| Tracheotomy after surgery | 0.498 | ||||
| No | 12 (85.71%) | 73 (67.59%) | 40 (64.52%) | 12 (66.67%) | |
| Yes | 2 (14.29%) | 35 (32.41%) | 22 (35.48%) | 6 (33.33%) | |
| Second intubation after surgery | 0.009 | ||||
| No | 2 (14.29%) | 41 (37.96%) | 35 (56.45%) | 10 (55.56%) | |
| Yes | 12 (85.71%) | 67 (62.04%) | 27 (43.55%) | 8 (44.44%) | |
| Survive | 0.009 | ||||
| No | 0 (0.00%) | 33 (30.56%) | 28 (45.16%) | 7 (38.89%) | |
| Yes | 14 (100.00%) | 75 (69.44%) | 34 (54.84%) | 11 (61.11%) | |
| EF – ejection fraction; COPD – chronic obstructive pulmonary disease; IBW – ideal body weight; AMI – acute myocardial infarction; CABG – coronary artery bypass grafting; APACHE – acute physiology and chronic health evaluation; ARDS – acute respiratory distress syndrome; IABP – intra-aortic balloon pump; ECMO – extracorporeal membrane oxygenation therapy; CRRT – continuous renal replacement therapy | |||||