25 August 2021: Clinical Research
“Obesity Paradox” in Acute Respiratory Distress Syndrome Among Patients Undergoing Cardiac Surgery: A Retrospective Study
Yan Liu 1ABCDEFG , Man Song 1BCDF , Lixue Huang 2BCDF , Guangfa Zhu 13ACG*DOI: 10.12659/MSM.931808
Med Sci Monit 2021; 27:e931808
Supplementary Table 1 Baseline characteristics of patients (n=1010).
| BMI | <18.5 | ≥18.5,<25 | ≥25,<30 | ≥30 | P value |
|---|---|---|---|---|---|
| N (%) | 41 (4.06%) | 548 (54.26%) | 357 (35.34%) | 64 (6.33%) | – |
| Age, years | 42.63±17.90 | 58.85±13.47 | 60.55±11.79 | 56.00±12.62 | |
| Smoking index | 250.0 (125.0–675.0) | 450.0 (210.0–800.0) | 500.0 (300.0–800.0) | 400.0 (210.0–800.0) | 0.517 |
| EF value before surgery, % | 61.24±8.80 | 60.29±10.19 | 60.06±8.74 | 60.22±9.81 | 0.934 |
| Hemoglobin level before surgery, g/l | 129.10±22.37 | 132.68±18.84 | 134.44±17.98 | 133.72±20.77 | 0.267 |
| Albumin level before surgery, g/l | 43.25±3.47 | 40.49±5.34 | 40.45±5.14 | 40.51±5.16 | 0.011 |
| APACHE II value | 15.54±3.56 | 16.64±3.68 | 16.81±3.67 | 17.12±4.88 | 0.167 |
| Duration of surgery, hours | 4.81±1.91 | 4.72±1.90 | 4.73±1.85 | 5.06±2.30 | 0.579 |
| Blood loss, ml | 600.00 (400.00–1000.00) | 600.00 (400.00–1000.00) | 700.00 (500.00–1000.00) | 600.00 (350.00–1000.00) | 0.383 |
| Transfusion of red blood cells, ml | 400.00 (200.00–600.00) | 400.00 (233.50–800.00) | 400.00 (239.00–770.00) | 400.00 (200.00–625.00) | 0.665 |
| Transfusion of plasma cells, ml | 0.00 (0.00–400.00) | 0.00 (0.00–400.00) | 0.00 (0.00–200.00) | 0.00 (0.00–0.00) | 0.048 |
| EF value after surgery, % | 50.50±18.33 | 48.52±22.70 | 46.16±23.33 | 49.91±21.14 | 0.458 |
| ARDS, % | 0.004 | ||||
| No | 26 (63.41%) | 445 (81.20%) | 293 (82.07%) | 44 (68.75%) | |
| Yes | 15 (36.59%) | 103 (18.80%) | 64 (17.93%) | 20 (31.25%) | |
| Gender, % | |||||
| Male | 24 (58.54%) | 351 (64.05%) | 272 (76.19%) | 43 (67.19%) | |
| Female | 17 (41.46%) | 197 (35.95%) | 85 (23.81%) | 21 (32.81%) | |
| History of cardiac surgery, % | 0.001 | ||||
| No | 37 (90.24%) | 522 (95.26%) | 354 (99.16%) | 63 (98.44%) | |
| Yes | 4 (9.76%) | 26 (4.74%) | 3 (0.84%) | 1 (1.56%) | |
| History of hypertension, % | |||||
| No | 38 (92.68%) | 334 (60.95%) | 160 (44.82%) | 25 (39.06%) | |
| Yes | 63 (7.32%) | 214 (39.05%) | 197 (55.18%) | 39 (60.94%) | |
| History of diabetes, % | 0.030 | ||||
| No | 37 (90.24%) | 464 (84.67%) | 281 (78.71%) | 57 (89.06%) | |
| Yes | 4 (9.76%) | 84 (15.33%) | 76 (21.29%) | 7 (10.94%) | |
| History of AMI, % | 0.004 | ||||
| No | 38 (92.68%) | 446 (81.39%) | 262 (73.39%) | 49 (76.56%) | |
| Yes | 3 (7.32%) | 102 (18.61%) | 95 (26.61%) | 15 (23.44%) | |
| Emergency surgery, % | 0.068 | ||||
| No | 41 (100.00%) | 523 (95.44%) | 338 (94.68%) | 57 (89.06%) | |
| Yes | 0 (0.00%) | 25 (4.56%) | 19 (5.32%) | 7 (10.94%) | |
| Type of surgery, % | |||||
| isolated valvular surgery or isolated CABG surgery | 22 (53.66%) | 421 (76.68%) | 281 (78.71%) | 42 (66.67%) | |
| Valvular combined with CABG surgery | 4 (9.76%) | 31 (5.65%) | 15 (4.20%) | 5 (7.94%) | |
| Aortic surgery | 1 (2.44%) | 28 (5.10%) | 24 (6.72%) | 11 (17.46%) | |
| Others | 14 (34.15%) | 69 (12.57%) | 37 (10.36%) | 5 (7.94%) | |
| EF – ejection fraction; COPD – chronic obstructive pulmonary disease; AMI – acute myocardial infarction; CABG – coronary artery bypass grafting; APACHE – acute physiology and chronic health evaluation; ARDS – acute respiratory distress syndrome. | |||||