Integrated Bioinformatic Analysis of Competing Endogenous RNA Network of Choriocarcinoma

20 September 2021: Database Analysis

Qianxia Tan ^ABE , Zhihui Tan ^BC , Junliang Liu ^CD , Yanqun Mo ^CF , Huining Liu ^AG*

DOI: 10.12659/MSM.931475

Med Sci Monit 2021; 27:e931475

Table 1 The enriched GO and KEGG term.

ID	Term	Count	P value

GO: 0007507	Heart development	11	1.27E-05
GO: 0001525	Angiogenesis	10	3.49E-04
GO: 0030324	Lung development	6	8.83E-04
GO: 0008283	Cell proliferation	12	9.56E-04
GO: 0043065	Positive regulation of apoptotic process	10	0.00279
GO: 0060068	Vagina development	3	0.00326
GO: 0046330	Positive regulation of jnk cascade	5	0.00374
GO: 0048048	Embryonic eye morphogenesis	3	0.00405
GO: 0032940	Secretion by cell	3	0.00405
GO: 0009749	Response to glucose	5	0.00440

GO: 0070062	Extracellular exosome	51	1.48E-06
GO: 0031012	Extracellular matrix	13	1.89E-05
GO: 0005578	Proteinaceous extracellular matrix	12	3.77E-05
GO: 0009986	Cell surface	15	4.79E-04
GO: 1903561	Extracellular vesicle	5	0.00113
MF
GO: 0005515	Protein binding	113	8.02E-05
GO: 0005520	Insulin-like growth factor binding	4	7.08E-04
GO: 0050840	Extracellular matrix binding	4	0.00213
GO: 0005201	Extracellular matrix structural constituent	5	0.00446
GO: 0004714	Transmembrane receptor protein tyrosine kinase activity	4	0.00633

hsa04550	Signaling pathways regulating pluripotency of stem cells	7	0.00493
hsa04115	p53 signaling pathway	4	0.04003
hsa05169	Epstein-Barr virus infection	5	0.04925
hsa04350	TGF-beta signaling pathway	4	0.06958
hsa04310	Wnt signaling pathway	5	0.07099
hsa04960	Aldosterone-regulated sodium reabsorption	3	0.07184
hsa05200	Pathways in cancer	9	0.07585
hsa05205	Proteoglycans in cancer	6	0.07597
hsa04978	Mineral absorption	3	0.0885
hsa04015	Rap1 signaling pathway	6	0.08924