14 August 2021: Database Analysis
Identification of Mucus-Associated Molecular Subtypes of Chronic Obstructive Pulmonary Disease: A Latent Profile Analysis Based on MUC5B-Associated Genes
Yuanlong Hu 1ACE* , Xiaomeng Cheng 1BCEF* , Zhanjun Qiu 2ADG* , Xianhai Chen 2ADFG*DOI: 10.12659/MSM.931222
Med Sci Monit 2021; 27:e931222
Supplementary Table 2 The source and detailed method of gene signature used to calculate ssgsea score.
| Immune score | Gene signature | Method | Source |
|---|---|---|---|
| Th1 cells | GSE14308_TH1_VS_NAIVE_CD4_TCELL_UP, GSE14308_TH1_VS_NAIVE_CD4_TCELL_DN | UP/DN | MSigDB-C7 |
| Activated Th1 cells | GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH1_DN, GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH1_UP | DN/UP | MSigDB-C7 |
| Th2 cells | GSE14308_TH2_VS_NAIVE_CD4_TCELL_UP, GSE14308_TH2_VS_NAIVE_CD4_TCELL_DN | UP/DN | MSigDB-C7 |
| Activated Th2 | GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH2_DN, GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH2_UP | DN/UP | MSigDB-C7 |
| Th1/Th2 | ---- | Th1 cells/Th2 cells | |
| Activated Th1/activated Th2 | Activated Th1 cells/activated Th2 cells | ||
| Macrophage M1 | GSE5099_MONOCYTE_VS_CLASSICAL_M1_MACROPHAGE_DN, GSE5099_MONOCYTE_VS_CLASSICAL_M1_MACROPHAGE_UP | DN/UP | MSigDB-C7 |
| Macrophage M2 | GSE5099_MONOCYTE_VS_ALTERNATIVE_M2_MACROPHAGE_DN, GSE5099_MONOCYTE_VS_ALTERNATIVE_M2_MACROPHAGE_UP | DN/UP | MSigDB-C7 |
| M1/M2 | ---- | Macrophage M1/ Macrophage M2 | ---- |
| Tregs | GSE15659_NAIVE_CD4_TCELL_VS_ACTIVATED_TREG_DN, GSE15659_NAIVE_CD4_TCELL_VS_ACTIVATED_TREG_UP | DN/UP | MSigDB-C7 |
| Th17 cells | GSE14308_TH17_VS_NAIVE_CD4_TCELL_UP, GSE14308_TH17_VS_NAIVE_CD4_TCELL_DN | UP/DN | MSigDB-C7 |
| Th17/Tregs | ---- | Th17 cells/Tregs | |
| Neutrophil | HAY_BONE_MARROW_NEUTROPHIL | ---- | MSigDB-C8 |
| Eosinophil | HAY_BONE_MARROW_EOSINOPHIL | ---- | MSigDB-C8 |
| Cilium movement | Cilium movement (GO: 0003341) | ---- | Gene Ontology-BP |